Psoriasis vulgaris is a persistent autoimmune illness related to systemic irritation. Increased ranges of quite a few cytokines, chemokines, progress components, and different molecules have been discovered in the pores and skin and in the circulation of psoriatic sufferers.
Alarmins, also called hazard indicators, are intracellular proteins, that are launched to an extracellular house after an infection or harm. They are the markers of cell harmful processes.The goal of the current examine was to judge the suitability of chosen alarmins (HMGB1, IL-33, S100A7, and S100A12) as potential biomarkers of severity of psoriasis and to discover potential relationships between these proteins for the aim of higher understanding their roles in the immunopathology of psoriasis.
The serum ranges of chosen alarmins have been measured in 63 psoriatic sufferers and 95 management people. The ranges have been assessed by the ELISA method utilizing industrial kits. The knowledge have been statistically processed with MedCalc model 19.0.5.
Results
In psoriatic sufferers, we discovered considerably elevated ranges of HMGB1 (p < 0.05), IL-33 (p < 0.01), S100A7 (p < 0.0001), and S100A12 (p < 0.0001). In addition, we discovered a big relationship between HMGB1 and S100A7 (Spearman’s rho = 0.276, p < 0.05) in the sufferers and vital relationship between HMGB1 and IL-33 in the controls (Spearman’s rho = 0.416, p < 0.05).
We didn’t discover any relationship between noticed alarmins and the illness severity.The alarmins HMGB1, IL-33, S100A7, and S100A12 have been considerably elevated in the serum of sufferers, which states the speculation that they play particular roles in the immunopathology of psoriasis. However, we’ve not but discovered a relationship between noticed alarmins and the illness severity. The discovery of the connection between HMGB1 and S100A7 is a novelty that must be studied in the long run to additional make clear its function and significance.
Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in creating neurons by concentrating on LATS2.
Propofol is an intravenous anesthetic agent that generally induces vital neuroapoptosis. MicroRNAs (miRNAs) have been reported to take part in the regulation of propofol exposure-mediated neurotoxicity. MiR-215, as considered one of miRNAs, was discovered to manage nerve cell survival. However, the mechanism via which miRNAs regulate propofol exposure-mediated neurotoxicity remains to be unclear.Real-time PCR was used to detect miR-215 expression stage. Cell viability was measured utilizing MTT assay.
Cell apoptosis was examined by way of move cytometry evaluation. ROS, MDA, LDH and SOD ranges have been assayed via ELISA kits. Dual luciferase reporter assay recognized the interplay between miR-215 and massive tumor suppressor 2 (LATS2). Protein stage was detected utilizing western blot evaluation.MiR-215 expression was downregulated in propofol-treated rat hippocampal neurons. MiR-215 mimics promoted cell viability and lowered apoptosis in propofol-treated neonatal rat hippocampal neuron.
 ELISA Kit) Human Nesfatin-1 (NK1) ELISA Kit |
|
MBS3802672-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 NK1 receptor antagonist 2 |
|
HY-145250 |
MedChemExpress |
1 mg |
EUR 5573.68 |
|
Description: NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss[1]. |
 (extracellular) Antibody) Polyclonal Neurokinin Receptor 1 (NK1) (extracellular) Antibody |
|
AMM06658G |
Leading Biology |
0.05ml |
EUR 790.8 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Neurokinin Receptor 1 (NK1) (extracellular) . This antibody is tested and proven to work in the following applications: |
 Human HGF/NK1 Recombinant Protein |
|
300-132 |
ReliaTech |
25 µg |
EUR 196.35 |
Human HGF/NK1 Recombinant Protein |
|
300-132S |
ReliaTech |
5 µg |
EUR 92.4 |
 Bovine HGF/NK1 Recombinant Protein |
|
300-133 |
ReliaTech |
25 µg |
EUR 196.35 |
Bovine HGF/NK1 Recombinant Protein |
|
300-133S |
ReliaTech |
5 µg |
EUR 92.4 |
 Antibody) NK1 Homeobox 2 (NKX1-2) Antibody |
|
abx026417-400l |
Abbexa |
400 µl |
EUR 518.75 |
NK1 Homeobox 2 (NKX1-2) Antibody |
|
abx026417-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
|
NK1 Homeobox 2 (NKX1-2) Antibody |
|
abx026417-80l |
Abbexa |
80 µl |
EUR 250 |
|
|
NK1 Homeobox 2 (NKX1-2) Antibody |
|
abx235749-100g |
Abbexa |
100 µg |
EUR 350 |
NK1 Homeobox 2 (NKX1-2) Antibody |
|
abx235749-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
|
) Recombinant Human NK1 protein (C-6His) |
|
CD01215-10ug |
Jiaxing Korain Biotech Ltd (BT Labs) |
10ug |
EUR 118 |
|
|
|
Description: Recombinant Human CD160 is produced by our Mammalian expression system and the target gene encoding Ile27-Ser159 is expressed with a 6His tag at the C-terminus. |
Recombinant Human NK1 protein (C-6His) |
|
CD01215-50ug |
Jiaxing Korain Biotech Ltd (BT Labs) |
50ug |
EUR 329 |
|
|
|
Description: Recombinant Human CD160 is produced by our Mammalian expression system and the target gene encoding Ile27-Ser159 is expressed with a 6His tag at the C-terminus. |
) Recombinant Mouse NK1 protein (C-6His) |
|
CD00286-10ug |
Jiaxing Korain Biotech Ltd (BT Labs) |
10ug |
EUR 212 |
|
|
|
Description: Recombinant Mouse CD160 Antigen is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus. |
Recombinant Mouse NK1 protein (C-6His) |
|
CD00286-50ug |
Jiaxing Korain Biotech Ltd (BT Labs) |
50ug |
EUR 588 |
|
|
|
Description: Recombinant Mouse CD160 Antigen is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus. |
) Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1) |
|
MBS1358515-002mgBaculovirus |
MyBiosource |
0.02mg(Baculovirus) |
EUR 1285 |
Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1) |
|
MBS1358515-002mgEColi |
MyBiosource |
0.02mg(E-Coli) |
EUR 960 |
Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1) |
|
MBS1358515-002mgYeast |
MyBiosource |
0.02mg(Yeast) |
EUR 1075 |
Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1) |
|
MBS1358515-01mgEColi |
MyBiosource |
0.1mg(E-Coli) |
EUR 1120 |
Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1) |
|
MBS1358515-01mgYeast |
MyBiosource |
0.1mg(Yeast) |
EUR 1225 |
 ELISA Kit) Human NK1 transcription factor-related protein 1 (NKX1-1) ELISA Kit |
|
abx535349-96tests |
Abbexa |
96 tests |
EUR 687.5 |
 Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit |
|
MBS9325644-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit |
|
MBS9325644-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit |
|
MBS9325644-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit |
|
MBS9325644-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 receptor (Tachykinin Receptor 1 Antibody), Polyclonal Antibody, Rabbit) Neurokinin-1 (NK1) receptor (Tachykinin Receptor 1 Antibody), Polyclonal Antibody, Rabbit |
|
MBS555172-01mL |
MyBiosource |
0.1mL |
EUR 440 |
Neurokinin-1 (NK1) receptor (Tachykinin Receptor 1 Antibody), Polyclonal Antibody, Rabbit |
|
MBS555172-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1840 |
 ELISA Kit) Human NK1 Homeobox 2 (NKX1-2) ELISA Kit |
|
abx381816-96tests |
Abbexa |
96 tests |
EUR 687.5 |
|
|
 - Mouse NK1 transcription factor related, locus 1 (Drosophila) (Nkx1-1)) Nkx1 (untagged) - Mouse NK1 transcription factor related, locus 1 (Drosophila) (Nkx1-1) |
|
MC227713 |
Origene Technologies GmbH |
10 µg |
Ask for price |
) Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor) |
|
MBS642554-005mL |
MyBiosource |
0.05mL |
EUR 835 |
Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor) |
|
MBS642554-5x005mL |
MyBiosource |
5x0.05mL |
EUR 3600 |
) CD160 (BY55, CD160 antigen, FLJ46513, Natural killer cell receptor BY55, NK1, NK28) |
|
MBS604685-02mg |
MyBiosource |
0.2mg |
EUR 705 |
CD160 (BY55, CD160 antigen, FLJ46513, Natural killer cell receptor BY55, NK1, NK28) |
|
MBS604685-5x02mg |
MyBiosource |
5x0.2mg |
EUR 3030 |
 - Mouse NK1 transcription factor related, locus 1 (Drosophila) (Nkx1-1)) Nkx1 (myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 1 (Drosophila) (Nkx1-1) |
|
MR229924 |
Origene Technologies GmbH |
10 µg |
Ask for price |
 (FITC)) CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (FITC) |
|
MBS607715-01mg |
MyBiosource |
0.1mg |
EUR 650 |
CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (FITC) |
|
MBS607715-5x01mg |
MyBiosource |
5x0.1mg |
EUR 2780 |
 Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit |
|
MBS9336355-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit |
|
MBS9336355-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit |
|
MBS9336355-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit |
|
MBS9336355-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 ELISA Kit) Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit |
|
MBS283750-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6840 |
Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit |
|
MBS283750-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 480 |
Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit |
|
MBS283750-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3610 |
Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit |
|
MBS283750-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 805 |
 Chicken NK1 transcription factor-related protein 2, SAX1 ELISA Kit |
|
MBS9339241-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
) Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2) |
|
MBS1446065-002mgBaculovirus |
MyBiosource |
0.02mg(Baculovirus) |
EUR 1190 |
Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2) |
|
MBS1446065-002mgEColi |
MyBiosource |
0.02mg(E-Coli) |
EUR 835 |
Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2) |
|
MBS1446065-002mgYeast |
MyBiosource |
0.02mg(Yeast) |
EUR 980 |
Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2) |
|
MBS1446065-01mgEColi |
MyBiosource |
0.1mg(E-Coli) |
EUR 1005 |
Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2) |
|
MBS1446065-01mgYeast |
MyBiosource |
0.1mg(Yeast) |
EUR 1120 |
) Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2) |
|
MBS961659-002mgBaculovirus |
MyBiosource |
0.02mg(Baculovirus) |
EUR 1185 |
Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2) |
|
MBS961659-002mgEColi |
MyBiosource |
0.02mg(E-Coli) |
EUR 830 |
Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2) |
|
MBS961659-002mgYeast |
MyBiosource |
0.02mg(Yeast) |
EUR 975 |
Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2) |
|
MBS961659-01mgEColi |
MyBiosource |
0.1mg(E-Coli) |
EUR 995 |
Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2) |
|
MBS961659-01mgYeast |
MyBiosource |
0.1mg(Yeast) |
EUR 1140 |
 (Azide Free)) CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (Azide Free) |
|
MBS605024-1mg |
MyBiosource |
1mg |
EUR 1055 |
CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (Azide Free) |
|
MBS605024-5x1mg |
MyBiosource |
5x1mg |
EUR 4600 |
 ELISA Kit) Mouse NK1 transcription factor-related protein 2 (NKX1-2) ELISA Kit |
|
abx535351-96tests |
Abbexa |
96 tests |
EUR 687.5 |
 Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9319882-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9319882-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9319882-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9319882-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9327743-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9327743-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9327743-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit |
|
MBS9327743-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), (10ug)) Nkx1 (untagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), (10ug) |
|
MC209354 |
Origene Technologies GmbH |
10 µg |
Ask for price |
) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) |
|
MBS6003640-02mL |
MyBiosource |
0.2(mL |
EUR 695 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) |
|
MBS6003640-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2975 |
 - Mouse NK1 transcription factor related locus 2 (Drosophila) (Nkx1-2), (10ug)) Nkx1 (GFP-tagged) - Mouse NK1 transcription factor related locus 2 (Drosophila) (Nkx1-2), (10ug) |
|
MG218057 |
Origene Technologies GmbH |
10 µg |
Ask for price |
 (AP)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (AP) |
|
MBS6325510-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (AP) |
|
MBS6325510-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (APC)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (APC) |
|
MBS6325511-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (APC) |
|
MBS6325511-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (FITC)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (FITC) |
|
MBS6325513-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (FITC) |
|
MBS6325513-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (PE)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (PE) |
|
MBS6325520-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (PE) |
|
MBS6325520-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2)) Nkx1 (Myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2) |
|
MR218057 |
Origene Technologies GmbH |
10 µg |
Ask for price |
 (Biotin)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Biotin) |
|
MBS6325512-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Biotin) |
|
MBS6325512-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) |
|
MBS6003495-02mL |
MyBiosource |
0.2(mL |
EUR 695 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) |
|
MBS6003495-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2975 |
 (MaxLight 405)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 405) |
|
MBS6325515-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 405) |
|
MBS6325515-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 490)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 490) |
|
MBS6325516-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 490) |
|
MBS6325516-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 550)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 550) |
|
MBS6325517-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 550) |
|
MBS6325517-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 650)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 650) |
|
MBS6325518-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 650) |
|
MBS6325518-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 750)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 750) |
|
MBS6325519-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 750) |
|
MBS6325519-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (Azide free) (HRP)) NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Azide free) (HRP) |
|
MBS6325514-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Azide free) (HRP) |
|
MBS6325514-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (AP)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (AP) |
|
MBS6325521-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (AP) |
|
MBS6325521-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (APC)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (APC) |
|
MBS6325522-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (APC) |
|
MBS6325522-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (PE)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (PE) |
|
MBS6325531-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (PE) |
|
MBS6325531-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (Biotin)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Biotin) |
|
MBS6325523-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Biotin) |
|
MBS6325523-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 (FITC)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (FITC) |
|
MBS6325524-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (FITC) |
|
MBS6325524-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 - Human NK1 homeobox 2 (NKX1-2), 200ul, >10^7 TU/mL) Lenti ORF particles, NKX1 (mGFP-tagged) - Human NK1 homeobox 2 (NKX1-2), 200ul, >10^7 TU/mL |
|
RC228244L4V |
Origene Technologies GmbH |
200 µl |
Ask for price |
 - Human NK1 homeobox 2 (NKX1-2), 200ul, >10^7 TU/mL) Lenti ORF particles, NKX1 (Myc-DDK tagged) - Human NK1 homeobox 2 (NKX1-2), 200ul, >10^7 TU/mL |
|
RC228244L3V |
Origene Technologies GmbH |
200 µl |
Ask for price |
 (MaxLight 405)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 405) |
|
MBS6325526-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 405) |
|
MBS6325526-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 490)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 490) |
|
MBS6325527-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 490) |
|
MBS6325527-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 550)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 550) |
|
MBS6325528-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 550) |
|
MBS6325528-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 650)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 650) |
|
MBS6325529-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 650) |
|
MBS6325529-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 (MaxLight 750)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 750) |
|
MBS6325530-01mL |
MyBiosource |
0.1mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 750) |
|
MBS6325530-5x01mL |
MyBiosource |
5x0.1mL |
EUR 4250 |
 - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2)) Lenti ORF clone of Nkx1 (mGFP-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2) |
|
MR218057L4 |
Origene Technologies GmbH |
10 µg |
Ask for price |
 (Azide free) (HRP)) NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Azide free) (HRP) |
|
MBS6325525-02mL |
MyBiosource |
0.2mL |
EUR 980 |
NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Azide free) (HRP) |
|
MBS6325525-5x02mL |
MyBiosource |
5x0.2mL |
EUR 4250 |
 - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2)) Lenti ORF clone of Nkx1 (Myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2) |
|
MR218057L3 |
Origene Technologies GmbH |
10 µg |
Ask for price |
 - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), 200ul, >10^7 TU/mL) Lenti ORF particles, Nkx1 (GFP-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), 200ul, >10^7 TU/mL |
|
MR218057L4V |
Origene Technologies GmbH |
200 µl |
Ask for price |
 - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), 200ul, >10^7 TU/mL) Lenti ORF particles, Nkx1 (Myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), 200ul, >10^7 TU/mL |
|
MR218057L3V |
Origene Technologies GmbH |
200 µl |
Ask for price |
 NK-1 Antagonist 1 |
|
MBS3844650-10mg |
MyBiosource |
10mg |
EUR 1905 |
NK-1 Antagonist 1 |
|
MBS3844650-1mg |
MyBiosource |
1mg |
EUR 430 |
NK-1 Antagonist 1 |
|
MBS3844650-5mg |
MyBiosource |
5mg |
EUR 1165 |
NK-1 Antagonist 1 |
|
MBS3844650-5x10mg |
MyBiosource |
5x10mg |
EUR 8565 |
NK-1 Antagonist 1 |
|
MBS5767203-5mg |
MyBiosource |
5mg |
EUR 915 |
NK-1 Antagonist 1 |
|
MBS5767203-5x5mg |
MyBiosource |
5x5mg |
EUR 3970 |
NK-1 Antagonist 1 |
|
T12233-10mg |
TargetMol Chemicals |
10mg |
Ask for price |
|
|
|
Description: NK-1 Antagonist 1 |
NK-1 Antagonist 1 |
|
T12233-1g |
TargetMol Chemicals |
1g |
Ask for price |
|
|
|
Description: NK-1 Antagonist 1 |
NK-1 Antagonist 1 |
|
T12233-1mg |
TargetMol Chemicals |
1mg |
Ask for price |
|
|
|
Description: NK-1 Antagonist 1 |
NK-1 Antagonist 1 |
|
T12233-50mg |
TargetMol Chemicals |
50mg |
Ask for price |
|
|
|
Description: NK-1 Antagonist 1 |
MiR-215 mimics additionally induced inhibition of oxidative stress as evidenced by suppression of ROS, MDA and LDH ranges in addition to improve of SOD stage. In addition, we discovered that enormous tumor suppressor 2 (LATS2) is a goal of miR-215 and miR-215 mimics decreased LATS2 stage in propofol-treated neonatal rat hippocampal neuron. Further, LATS2 overexpression suppressed the impact of miR-215 on propofol-induced apoptosis and oxidative stress in neonatal rat hippocampal neuron.
Taken collectively, we exhibit that miR-215 attenuates propofol-induced apoptosis and oxidative stress in neonatal rat hippocampal neuron by concentrating on LATS2, suggesting that miR-215 could present a brand new candidate for the remedy of propofol exposure-induced neurotoxicity.
