Alarmins HMGB1, IL-33, S100A7, and S100A12 in Psoriasis Vulgaris.

Psoriasis vulgaris is a persistent autoimmune illness related to systemic irritation. Increased ranges of quite a few cytokines, chemokines, progress components, and different molecules have been discovered in the pores and skin and in the circulation of psoriatic sufferers.

Alarmins, also called hazard indicators, are intracellular proteins, that are launched to an extracellular house after an infection or harm. They are the markers of cell harmful processes.The goal of the current examine was to judge the suitability of chosen alarmins (HMGB1, IL-33, S100A7, and S100A12) as potential biomarkers of severity of psoriasis and to discover potential relationships between these proteins for the aim of higher understanding their roles in the immunopathology of psoriasis.

The serum ranges of chosen alarmins have been measured in 63 psoriatic sufferers and 95 management people. The ranges have been assessed by the ELISA method utilizing industrial kits. The knowledge have been statistically processed with MedCalc model 19.0.5.

Results

In psoriatic sufferers, we discovered considerably elevated ranges of HMGB1 (p < 0.05), IL-33 (p < 0.01), S100A7 (p < 0.0001), and S100A12 (p < 0.0001). In addition, we discovered a big relationship between HMGB1 and S100A7 (Spearman’s rho = 0.276, p < 0.05) in the sufferers and vital relationship between HMGB1 and IL-33 in the controls (Spearman’s rho = 0.416, p < 0.05).

We didn’t discover any relationship between noticed alarmins and the illness severity.The alarmins HMGB1, IL-33, S100A7, and S100A12 have been considerably elevated in the serum of sufferers, which states the speculation that they play particular roles in the immunopathology of psoriasis. However, we’ve not but discovered a relationship between noticed alarmins and the illness severity. The discovery of the connection between HMGB1 and S100A7 is a novelty that must be studied in the long run to additional make clear its function and significance.


Upregulation of miR-215 attenuates propofol-induced apoptosis and oxidative stress in creating neurons by concentrating on LATS2.

Propofol is an intravenous anesthetic agent that generally induces vital neuroapoptosis. MicroRNAs (miRNAs) have been reported to take part in the regulation of propofol exposure-mediated neurotoxicity. MiR-215, as considered one of miRNAs, was discovered to manage nerve cell survival. However, the mechanism via which miRNAs regulate propofol exposure-mediated neurotoxicity remains to be unclear.Real-time PCR was used to detect miR-215 expression stage. Cell viability was measured utilizing MTT assay.

Cell apoptosis was examined by way of move cytometry evaluation. ROS, MDA, LDH and SOD ranges have been assayed via ELISA kits. Dual luciferase reporter assay recognized the interplay between miR-215 and massive tumor suppressor 2 (LATS2). Protein stage was detected utilizing western blot evaluation.MiR-215 expression was downregulated in propofol-treated rat hippocampal neurons. MiR-215 mimics promoted cell viability and lowered apoptosis in propofol-treated neonatal rat hippocampal neuron.

Human Nesfatin-1 (NK1) ELISA Kit

MBS3802672-96StripWells 96-Strip-Wells
EUR 765

NK1 receptor antagonist 2

HY-145250 1 mg
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Description: NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss[1].

NKX1 (untagged) - Human NK1 homeobox 1 (NKX1-1)

SC336185 10 µg Ask for price

Polyclonal Neurokinin Receptor 1 (NK1) (extracellular) Antibody

AMM06658G 0.05ml
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Neurokinin Receptor 1 (NK1) (extracellular) . This antibody is tested and proven to work in the following applications:

Human HGF/NK1 Recombinant Protein

300-132 25 µg
EUR 196.35

Human HGF/NK1 Recombinant Protein

300-132S 5 µg
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Bovine HGF/NK1 Recombinant Protein

300-133 25 µg
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Bovine HGF/NK1 Recombinant Protein

300-133S 5 µg
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Rabbit polyclonal Anti-Neurokinin Receptor 1 (NK1) (extracellular)

TA329063 200 µl Ask for price

NK1 Homeobox 2 (NKX1-2) Antibody

abx026417-400l 400 µl
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NK1 Homeobox 2 (NKX1-2) Antibody

abx026417-400ul 400 ul
EUR 627.6

NK1 Homeobox 2 (NKX1-2) Antibody

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NK1 Homeobox 2 (NKX1-2) Antibody

abx235749-100g 100 µg
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NK1 Homeobox 2 (NKX1-2) Antibody

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NKX1 (myc-DDK-tagged) - Human NK1 homeobox 1 (NKX1-1)

RC238291 10 µg Ask for price

Recombinant Human NK1 protein (C-6His)

CD01215-10ug 10ug
EUR 118
Description: Recombinant Human CD160 is produced by our Mammalian expression system and the target gene encoding Ile27-Ser159 is expressed with a 6His tag at the C-terminus.

Recombinant Human NK1 protein (C-6His)

CD01215-50ug 50ug
EUR 329
Description: Recombinant Human CD160 is produced by our Mammalian expression system and the target gene encoding Ile27-Ser159 is expressed with a 6His tag at the C-terminus.

Recombinant Mouse NK1 protein (C-6His)

CD00286-10ug 10ug
EUR 212
Description: Recombinant Mouse CD160 Antigen is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus.

Recombinant Mouse NK1 protein (C-6His)

CD00286-50ug 50ug
EUR 588
Description: Recombinant Mouse CD160 Antigen is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus.

Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1)

MBS1358515-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1285

Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1)

MBS1358515-002mgEColi 0.02mg(E-Coli)
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Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1)

MBS1358515-002mgYeast 0.02mg(Yeast)
EUR 1075

Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1)

MBS1358515-01mgEColi 0.1mg(E-Coli)
EUR 1120

Recombinant Human NK1 transcription factor-related protein 1 (NKX1-1)

MBS1358515-01mgYeast 0.1mg(Yeast)
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Human NK1 transcription factor-related protein 1 (NKX1-1) ELISA Kit

abx535349-96tests 96 tests
EUR 687.5

Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit

MBS9325644-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit

MBS9325644-48StripWells 48-Strip-Wells
EUR 550

Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit

MBS9325644-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human NK1 transcription factor-related protein 1, NKX1-1 ELISA Kit

MBS9325644-96StripWells 96-Strip-Wells
EUR 765

Neurokinin-1 (NK1) receptor (Tachykinin Receptor 1 Antibody), Polyclonal Antibody, Rabbit

MBS555172-01mL 0.1mL
EUR 440

Neurokinin-1 (NK1) receptor (Tachykinin Receptor 1 Antibody), Polyclonal Antibody, Rabbit

MBS555172-5x01mL 5x0.1mL
EUR 1840

Human NK1 Homeobox 2 (NKX1-2) ELISA Kit

abx381816-96tests 96 tests
EUR 687.5

Nkx1 (untagged) - Rat NK1 homeobox 2 (Nkx1-2)

RN216297 10 µg Ask for price

NKX1 (untagged)-Human NK1 homeobox 2 (NKX1-2)

SC326879 10 µg Ask for price

Nkx1 (untagged) - Mouse NK1 transcription factor related, locus 1 (Drosophila) (Nkx1-1)

MC227713 10 µg Ask for price

NKX1 (GFP-tagged) - Human NK1 homeobox 2 (NKX1-2)

RG228244 10 µg Ask for price

Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)

MBS642554-005mL 0.05mL
EUR 835

Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)

MBS642554-5x005mL 5x0.05mL
EUR 3600

CD160 (BY55, CD160 antigen, FLJ46513, Natural killer cell receptor BY55, NK1, NK28)

MBS604685-02mg 0.2mg
EUR 705

CD160 (BY55, CD160 antigen, FLJ46513, Natural killer cell receptor BY55, NK1, NK28)

MBS604685-5x02mg 5x0.2mg
EUR 3030

Nkx1 (myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 1 (Drosophila) (Nkx1-1)

MR229924 10 µg Ask for price

Nkx1 (myc-DDK-tagged) - Rat NK1 homeobox 2 (Nkx1-2)

RR216297 10 µg Ask for price

NKX1 (Myc-DDK-tagged)-Human NK1 homeobox 2 (NKX1-2)

RC228244 10 µg Ask for price

CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (FITC)

MBS607715-01mg 0.1mg
EUR 650

CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (FITC)

MBS607715-5x01mg 5x0.1mg
EUR 2780

Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit

MBS9336355-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit

MBS9336355-48StripWells 48-Strip-Wells
EUR 550

Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit

MBS9336355-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human NK1 transcription factor-related protein 2, SAX1 ELISA Kit

MBS9336355-96StripWells 96-Strip-Wells
EUR 765

Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit

MBS283750-10x96StripWells 10x96-Strip-Wells
EUR 6840

Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit

MBS283750-48StripWells 48-Strip-Wells
EUR 480

Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit

MBS283750-5x96StripWells 5x96-Strip-Wells
EUR 3610

Chicken NK1 transcription factor-related protein 2 (SAX1) ELISA Kit

MBS283750-96StripWells 96-Strip-Wells
EUR 805

Chicken NK1 transcription factor-related protein 2, SAX1 ELISA Kit

MBS9339241-INQUIRE INQUIRE Ask for price

Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2)

MBS1446065-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1190

Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2)

MBS1446065-002mgEColi 0.02mg(E-Coli)
EUR 835

Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2)

MBS1446065-002mgYeast 0.02mg(Yeast)
EUR 980

Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2)

MBS1446065-01mgEColi 0.1mg(E-Coli)
EUR 1005

Recombinant Human NK1 transcription factor-related protein 2 (NKX1-2)

MBS1446065-01mgYeast 0.1mg(Yeast)
EUR 1120

Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2)

MBS961659-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1185

Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2)

MBS961659-002mgEColi 0.02mg(E-Coli)
EUR 830

Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2)

MBS961659-002mgYeast 0.02mg(Yeast)
EUR 975

Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2)

MBS961659-01mgEColi 0.1mg(E-Coli)
EUR 995

Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2)

MBS961659-01mgYeast 0.1mg(Yeast)
EUR 1140

CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (Azide Free)

MBS605024-1mg 1mg
EUR 1055

CD160 (BY55, CD160 Antigen, FLJ46513, Natural Killer Cell Receptor BY55, NK1, NK28) (Azide Free)

MBS605024-5x1mg 5x1mg
EUR 4600

Mouse NK1 transcription factor-related protein 2 (NKX1-2) ELISA Kit

abx535351-96tests 96 tests
EUR 687.5

Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9319882-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9319882-48StripWells 48-Strip-Wells
EUR 550

Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9319882-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9319882-96StripWells 96-Strip-Wells
EUR 765

Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9327743-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9327743-48StripWells 48-Strip-Wells
EUR 550

Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9327743-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human NK1 transcription factor-related protein 2, NKX1-2 ELISA Kit

MBS9327743-96StripWells 96-Strip-Wells
EUR 765

Lenti ORF clone of Human NK1 homeobox 2 (NKX1-2), mGFP tagged

RC228244L4 10 µg Ask for price

Lenti ORF clone of Human NK1 homeobox 2 (NKX1-2), Myc-DDK-tagged

RC228244L3 10 µg Ask for price

Nkx1 (untagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), (10ug)

MC209354 10 µg Ask for price

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1)

MBS6003640-02mL 0.2(mL
EUR 695

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1)

MBS6003640-5x02mL 5x0.2mL
EUR 2975

Nkx1 (GFP-tagged) - Mouse NK1 transcription factor related locus 2 (Drosophila) (Nkx1-2), (10ug)

MG218057 10 µg Ask for price

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (AP)

MBS6325510-02mL 0.2mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (AP)

MBS6325510-5x02mL 5x0.2mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (APC)

MBS6325511-02mL 0.2mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (APC)

MBS6325511-5x02mL 5x0.2mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (FITC)

MBS6325513-02mL 0.2mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (FITC)

MBS6325513-5x02mL 5x0.2mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (PE)

MBS6325520-02mL 0.2mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (PE)

MBS6325520-5x02mL 5x0.2mL
EUR 4250

Nkx1 (Myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2)

MR218057 10 µg Ask for price

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Biotin)

MBS6325512-02mL 0.2mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Biotin)

MBS6325512-5x02mL 5x0.2mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1)

MBS6003495-02mL 0.2(mL
EUR 695

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1)

MBS6003495-5x02mL 5x0.2mL
EUR 2975

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 405)

MBS6325515-01mL 0.1mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 405)

MBS6325515-5x01mL 5x0.1mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 490)

MBS6325516-01mL 0.1mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 490)

MBS6325516-5x01mL 5x0.1mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 550)

MBS6325517-01mL 0.1mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 550)

MBS6325517-5x01mL 5x0.1mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 650)

MBS6325518-01mL 0.1mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 650)

MBS6325518-5x01mL 5x0.1mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 750)

MBS6325519-01mL 0.1mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (MaxLight 750)

MBS6325519-5x01mL 5x0.1mL
EUR 4250

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Azide free) (HRP)

MBS6325514-02mL 0.2mL
EUR 980

NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (Azide free) (HRP)

MBS6325514-5x02mL 5x0.2mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (AP)

MBS6325521-02mL 0.2mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (AP)

MBS6325521-5x02mL 5x0.2mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (APC)

MBS6325522-02mL 0.2mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (APC)

MBS6325522-5x02mL 5x0.2mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (PE)

MBS6325531-02mL 0.2mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (PE)

MBS6325531-5x02mL 5x0.2mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Biotin)

MBS6325523-02mL 0.2mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Biotin)

MBS6325523-5x02mL 5x0.2mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (FITC)

MBS6325524-02mL 0.2mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (FITC)

MBS6325524-5x02mL 5x0.2mL
EUR 4250

Lenti ORF particles, NKX1 (mGFP-tagged) - Human NK1 homeobox 2 (NKX1-2), 200ul, >10^7 TU/mL

RC228244L4V 200 µl Ask for price

Lenti ORF particles, NKX1 (Myc-DDK tagged) - Human NK1 homeobox 2 (NKX1-2), 200ul, >10^7 TU/mL

RC228244L3V 200 µl Ask for price

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 405)

MBS6325526-01mL 0.1mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 405)

MBS6325526-5x01mL 5x0.1mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 490)

MBS6325527-01mL 0.1mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 490)

MBS6325527-5x01mL 5x0.1mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 550)

MBS6325528-01mL 0.1mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 550)

MBS6325528-5x01mL 5x0.1mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 650)

MBS6325529-01mL 0.1mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 650)

MBS6325529-5x01mL 5x0.1mL
EUR 4250

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 750)

MBS6325530-01mL 0.1mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (MaxLight 750)

MBS6325530-5x01mL 5x0.1mL
EUR 4250

Lenti ORF clone of Nkx1 (mGFP-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2)

MR218057L4 10 µg Ask for price

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Azide free) (HRP)

MBS6325525-02mL 0.2mL
EUR 980

NKX1-2, NT (NKX1-2, C10orf121, NKX1.1, NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1) (Azide free) (HRP)

MBS6325525-5x02mL 5x0.2mL
EUR 4250

Lenti ORF clone of Nkx1 (Myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2)

MR218057L3 10 µg Ask for price

Lenti ORF particles, Nkx1 (GFP-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), 200ul, >10^7 TU/mL

MR218057L4V 200 µl Ask for price

Lenti ORF particles, Nkx1 (Myc-DDK-tagged) - Mouse NK1 transcription factor related, locus 2 (Drosophila) (Nkx1-2), 200ul, >10^7 TU/mL

MR218057L3V 200 µl Ask for price

NK-1 Antagonist 1

MBS3844650-10mg 10mg
EUR 1905

NK-1 Antagonist 1

MBS3844650-1mg 1mg
EUR 430

NK-1 Antagonist 1

MBS3844650-5mg 5mg
EUR 1165

NK-1 Antagonist 1

MBS3844650-5x10mg 5x10mg
EUR 8565

NK-1 Antagonist 1

MBS5767203-5mg 5mg
EUR 915

NK-1 Antagonist 1

MBS5767203-5x5mg 5x5mg
EUR 3970

NK-1 Antagonist 1

T12233-10mg 10mg Ask for price
Description: NK-1 Antagonist 1

NK-1 Antagonist 1

T12233-1g 1g Ask for price
Description: NK-1 Antagonist 1

NK-1 Antagonist 1

T12233-1mg 1mg Ask for price
Description: NK-1 Antagonist 1

NK-1 Antagonist 1

T12233-50mg 50mg Ask for price
Description: NK-1 Antagonist 1

MiR-215 mimics additionally induced inhibition of oxidative stress as evidenced by suppression of ROS, MDA and LDH ranges in addition to improve of SOD stage. In addition, we discovered that enormous tumor suppressor 2 (LATS2) is a goal of miR-215 and miR-215 mimics decreased LATS2 stage in propofol-treated neonatal rat hippocampal neuron. Further, LATS2 overexpression suppressed the impact of miR-215 on propofol-induced apoptosis and oxidative stress in neonatal rat hippocampal neuron.

Taken collectively, we exhibit that miR-215 attenuates propofol-induced apoptosis and oxidative stress in neonatal rat hippocampal neuron by concentrating on LATS2, suggesting that miR-215 could present a brand new candidate for the remedy of propofol exposure-induced neurotoxicity.

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