The use of synthetic hormones to regulate sexual maturity in captive fish is a common practice. With aquaculture practices, fish production is desired throughout the year, necessitating the maintenance of quality standards, mainly regarding the characteristics of the fish produced.
Embryonic development may be affected by toxins in the environment and by a variety of pathologies. The aim of this study was to determine the effects of treatment with gonadotropin-releasing hormone analog (GnRHa) on captive male and female Atlantic Salmon (Salmo salar) broodstock, observing the effects on the hormonal milieu and impacts on breeding outcomes. Sexually mature fish were fertilized with and without imposing a GnRHa treatment to evaluate the development of offspring up to the fry stage.
 anti-CD45 RA B-cells, T-cells, NK-cells |
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| 516-A-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: anti-CD45 RA B-cells, T-cells, NK-cells |
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anti-CD45 RA B-cells, T-cells, NK-cells |
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| 516-A-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: anti-CD45 RA B-cells, T-cells, NK-cells |
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 5637 cells |
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| C0002001 | Addexbio | One Frozen vial | EUR 485 |
 MB49 cells |
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| C0002004 | Addexbio | One Frozen vial | EUR 777 |
 K562 cells |
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| C0003004 | Addexbio | One Frozen vial | EUR 455 |
 U937 cells |
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| C0003005 | Addexbio | One Frozen vial | EUR 455 |
 Raji cells |
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| C0003009 | Addexbio | One Frozen vial | EUR 455 |
 Daudi cells |
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| C0003010 | Addexbio | One Frozen vial | EUR 455 |
 RS4;11 cells |
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| C0003012 | Addexbio | One Frozen vial | EUR 455 |
 NAMALWA cells |
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| C0003013 | Addexbio | One Frozen vial | EUR 455 |
 BJAB cells |
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| C0003016 | Addexbio | One Frozen vial | EUR 543 |
 FO cells |
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| C0003017 | Addexbio | One Frozen vial | EUR 485 |
 MC116 cells |
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| C0003021 | Addexbio | One Frozen vial | EUR 485 |
 P3X63Ag8.653 cells |
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| C0003028 | Addexbio | One Frozen vial | EUR 455 |
 REH cells |
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| C0003031 | Addexbio | One Frozen vial | EUR 485 |
 Mino cells |
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| C0003033 | Addexbio | One Frozen vial | EUR 485 |
 U87MG cells |
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| C0005002 | Addexbio | One Frozen vial | EUR 455 |
 B103 cells |
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| C0005003 | Addexbio | One Frozen vial | EUR 777 |
 T47D cells |
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| C0006001 | Addexbio | One Frozen vial | EUR 455 |
 4T1 cells |
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| C0006004 | Addexbio | One Frozen vial | EUR 455 |
 HeLa cells |
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| C0008001 | Addexbio | One Frozen vial | EUR 455 |
 SiHa cells |
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| C0008002 | Addexbio | One Frozen vial | EUR 455 |
 C33A cells |
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| C0008003 | Addexbio | One Frozen vial | EUR 455 |
 CaSKi cells |
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| C0008004 | Addexbio | One Frozen vial | EUR 455 |
 SW480 cells |
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| C0009001 | Addexbio | One Frozen vial | EUR 455 |
 SW620 cells |
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| C0009002 | Addexbio | One Frozen vial | EUR 455 |
 T84 cells |
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| C0009008 | Addexbio | One Frozen vial | EUR 455 |
 HCT15 cells |
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| C0009010 | Addexbio | One Frozen vial | EUR 455 |
 LoVo cells |
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| C0009011 | Addexbio | One Frozen vial | EUR 455 |
 RKO cells |
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| C0009012 | Addexbio | One Frozen vial | EUR 455 |
 SW48 cells |
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| C0009014 | Addexbio | One Frozen vial | EUR 455 |
 SW1116 cells |
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| C0009019 | Addexbio | One Frozen vial | EUR 455 |
 H716 cells |
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| C0009022 | Addexbio | One Frozen vial | EUR 543 |
 OE33 cells |
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| C0013003 | Addexbio | One Frozen vial | EUR 660 |
 JROECL33 cells |
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| C0013004 | Addexbio | One Frozen vial | EUR 660 |
 Hep3B cells |
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| C0015001 | Addexbio | One Frozen vial | EUR 455 |
 HepG2 cells |
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| C0015002 | Addexbio | One Frozen vial | EUR 455 |
 Calu3 cells |
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| C0016001 | Addexbio | One Frozen vial | EUR 455 |
 A549 cells |
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| C0016002 | Addexbio | One Frozen vial | EUR 455 |
 H460 cells |
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| C0016003 | Addexbio | One Frozen vial | EUR 455 |
 A427 cells |
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| C0016004 | Addexbio | One Frozen vial | EUR 455 |
 H23 cells |
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| C0016005 | Addexbio | One Frozen vial | EUR 455 |
 H1703 cells |
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| C0016008 | Addexbio | One Frozen vial | EUR 543 |
 SW1573 cells |
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| C0016009 | Addexbio | One Frozen vial | EUR 543 |
 H520 cells |
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| C0016010 | Addexbio | One Frozen vial | EUR 455 |
 H226 cells |
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| C0016011 | Addexbio | One Frozen vial | EUR 455 |
 HCC4006 cells |
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| C0016012 | Addexbio | One Frozen vial | EUR 455 |
 H1975 cells |
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| C0016013 | Addexbio | One Frozen vial | EUR 543 |
 H1650 cells |
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| C0016015 | Addexbio | One Frozen vial | EUR 543 |
 H358 cells |
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| C0016016 | Addexbio | One Frozen vial | EUR 455 |
 H2228 cells |
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| C0016017 | Addexbio | One Frozen vial | EUR 543 |
 H2170 cells |
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| C0016018 | Addexbio | One Frozen vial | EUR 455 |
 H441 cells |
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| C0016019 | Addexbio | One Frozen vial | EUR 455 |
 H596 cells |
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| C0016020 | Addexbio | One Frozen vial | EUR 455 |
 H1581 cells |
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| C0016028 | Addexbio | One Frozen vial | EUR 543 |
 H2444 cells |
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| C0016038 | Addexbio | One Frozen vial | EUR 543 |
 H69AR cells |
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| C0016046 | Addexbio | One Frozen vial | EUR 543 |
 H1373 cells |
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| C0016047 | Addexbio | One Frozen vial | EUR 543 |
 H2122 cells |
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| C0016048 | Addexbio | One Frozen vial | EUR 543 |
 H526 cells |
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| C0016052 | Addexbio | One Frozen vial | EUR 455 |
 H1299 cells |
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| C0016053 | Addexbio | One Frozen vial | EUR 455 |
 H446 cells |
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| C0016054 | Addexbio | One Frozen vial | EUR 543 |
 H1770 cells |
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| C0016057 | Addexbio | One Frozen vial | EUR 543 |
 H1184 cells |
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| C0016058 | Addexbio | One Frozen vial | EUR 543 |
 H1694 cells |
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| C0016060 | Addexbio | One Frozen vial | EUR 543 |
 H187 cells |
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| C0016061 | Addexbio | One Frozen vial | EUR 455 |
 H1963 cells |
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| C0016062 | Addexbio | One Frozen vial | EUR 543 |
 H209 cells |
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| C0016063 | Addexbio | One Frozen vial | EUR 455 |
 H69 cells |
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| C0016065 | Addexbio | One Frozen vial | EUR 455 |
 H82 cells |
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| C0016066 | Addexbio | One Frozen vial | EUR 455 |
 H847 cells |
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| C0016067 | Addexbio | One Frozen vial | EUR 543 |
 H660 cells |
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| C0016068 | Addexbio | One Frozen vial | EUR 695 |
 SW1271 cells |
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| C0016073 | Addexbio | One Frozen vial | EUR 543 |
 A673 cells |
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| C0016074 | Addexbio | One Frozen vial | EUR 455 |
 H524 cells |
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| C0016077 | Addexbio | One Frozen vial | EUR 543 |
 H211 cells |
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| C0016078 | Addexbio | One Frozen vial | EUR 543 |
 H146 cells |
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| C0016080 | Addexbio | One Frozen vial | EUR 455 |
 H889 cells |
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| C0016081 | Addexbio | One Frozen vial | EUR 543 |
 H510A cells |
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| C0016082 | Addexbio | One Frozen vial | EUR 455 |
 H128 cells |
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| C0016083 | Addexbio | One Frozen vial | EUR 543 |
 H1048 cells |
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| C0016084 | Addexbio | One Frozen vial | EUR 543 |
 A2780 cells |
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| C0017002 | Addexbio | One Frozen vial | EUR 543 |
 A2780cis cells |
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| C0017003 | Addexbio | One Frozen vial | EUR 602 |
 E3LZ10.7 cells |
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| C0018005 | Addexbio | One Frozen vial | EUR 660 |
 A10.7 cells |
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| C0018006 | Addexbio | One Frozen vial | EUR 660 |
 Vcap cells |
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| C0019001 | Addexbio | One Frozen vial | EUR 455 |
 C32 cells |
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| C0020002 | Addexbio | One Frozen vial | EUR 455 |
 N87 cells |
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| C0023002 | Addexbio | One Frozen vial | EUR 455 |
 AGS cells |
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| C0023004 | Addexbio | One Frozen vial | EUR 455 |
 8505C cells |
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| C0025002 | Addexbio | One Frozen vial | EUR 660 |
 K1 cells |
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| C0025003 | Addexbio | One Frozen vial | EUR 660 |
 R2C cells |
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| C0028001 | Addexbio | One Frozen vial | EUR 543 |
 Y79 cells |
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| C0029001 | Addexbio | One Frozen vial | EUR 455 |
 BeWo cells |
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| C0030001 | Addexbio | One Frozen vial | EUR 455 |
 T11D7e2 cells |
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| C0033001 | Addexbio | One Frozen vial | EUR 602 |
 NB3 cells |
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| C0033003 | Addexbio | One Frozen vial | EUR 660 |
 RD cells |
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| C0035001 | Addexbio | One Frozen vial | EUR 455 |
 HASM cells |
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| P0001001 | Addexbio | One Frozen vial | EUR 777 |
 HBSM cells |
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| P0007001 | Addexbio | One Frozen vial | EUR 777 |
 SCBN cells |
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| P0010001 | Addexbio | One Frozen vial | EUR 543 |
 STO cells |
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| P0011006 | Addexbio | One Frozen vial | EUR 455 |
 A9 cells |
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| P0011007 | Addexbio | One Frozen vial | EUR 543 |
 L929 cells |
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| P0011012 | Addexbio | One Frozen vial | EUR 455 |
 MDCKII cells |
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| P0014001 | Addexbio | One Frozen vial | EUR 455 |
 VERO cells |
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| P0014002 | Addexbio | One Frozen vial | EUR 455 |
 MDCK cells |
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| P0014003 | Addexbio | One Frozen vial | EUR 455 |
 BJ cells |
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| P0020005 | Addexbio | One Frozen vial | EUR 455 |
 HUVEC cells |
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| P0027001 | Addexbio | One Frozen vial | EUR 485 |
 C2C12 cells |
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| P0028001 | Addexbio | One Frozen vial | EUR 455 |
 ST cells |
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| P0028002 | Addexbio | One Frozen vial | EUR 543 |
 C127 cells |
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| S0006001 | Addexbio | One Frozen vial | EUR 485 |
 hFOB1.19 cells |
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| T0004005 | Addexbio | One Frozen vial | EUR 455 |
 SVGp12 cells |
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| T0005008 | Addexbio | One Frozen vial | EUR 543 |
 BSC40 cells |
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| T0011003 | Addexbio | One Frozen vial | EUR 543 |
 Mv1Lu cells |
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| T0016003 | Addexbio | One Frozen vial | EUR 455 |
 IMCC3 cells |
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| T0017001 | Addexbio | One Frozen vial | EUR 719 |
 HPDEC cells |
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| T0018001 | Addexbio | One Frozen vial | EUR 777 |
 HaCaT cells |
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| T0020001 | Addexbio | One Frozen vial | EUR 719 |
 Hs27 cells |
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| T0020010 | Addexbio | One Frozen vial | EUR 455 |
 TM3 cells |
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| T0028002 | Addexbio | One Frozen vial | EUR 455 |
) Neural Stem Cells (iPSC from Blood Cells; Male) |
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| ASE-9234 | Applied StemCell | 1 vial (1 x 10^6) | EUR 414.5 |
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Description: 12 month |
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) Neural Stem Cells (iPSC from Blood Cells; Female) |
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| ASE-9234F | Applied StemCell | 1 vial (1 x 10^6) | EUR 414.5 |
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Description: 12 month |
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 Human Cord Blood CD34+ Cells Derived Endothelial Cells |
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| HEC23 | Neuromics | 500,000+ Cells | EUR 1080 |
, Cryopreserved) Human CD3+ T Cells (Pan T Cells), Cryopreserved |
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| M1299-10 | Biovision | EUR 566 | |
Human CD3+ T Cells (Pan T Cells), Cryopreserved |
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| M1299-20 | Biovision | EUR 805 | |
Human CD3+ T Cells (Pan T Cells), Cryopreserved |
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| M1299-30 | Biovision | EUR 1327 | |
Human CD3+ T Cells (Pan T Cells), Cryopreserved |
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| M1299-40 | Biovision | EUR 1953 | |
 Mitotic Cells antibody |
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| 10R-8086 | Fitzgerald | 100 ug | EUR 467 |
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Description: Mouse monoclonal Mitotic Cells antibody |
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 MEF Feeder Cells |
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| CBA-310 | Cell Biolabs | 1 vial | EUR 392 |
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Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells. |
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 JK1 Feeder Cells |
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| CBA-315 | Cell Biolabs | 1 vial | EUR 769 |
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Description: JK1 Feeder Cells are used for the maintenance of numerous types of stem cells in their undifferentiated state. The cells must be mitotically inactivated prior to the addition of ES cells, such as treatment with mitomycin C (2-4 hr, 10 µg/mL). |
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 SNL Feeder Cells |
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| CBA-316 | Cell Biolabs | 1 vial | EUR 769 |
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Description: The SNL 76/7 cell line, established by Dr. Allan Bradley, is clonally derived from a mouse fibroblast STO cell line transformed with neomycin resistance and murine LIF genes. SNL can be used as a feeder cell for ES cell growth, and it also has been recently used in mouse or human iPS culture. |
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 CCRF-CEM cells |
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| C0003001 | Addexbio | One Frozen vial | EUR 455 |
 RPMI-8226 cells |
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| C0003002 | Addexbio | One Frozen vial | EUR 455 |
 MOLM-13 cells |
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| C0003003 | Addexbio | One Frozen vial | EUR 543 |
 LP-1 cells |
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| C0003006 | Addexbio | One Frozen vial | EUR 543 |
 PBL-2H3 cells |
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| C0003007 | Addexbio | One Frozen vial | EUR 455 |
 RAW 264.7 cells |
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| C0003008 | Addexbio | One Frozen vial | EUR 455 |
 F-36P cells |
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| C0003014 | Addexbio | One Frozen vial | EUR 543 |
 SD-1 cells |
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| C0003015 | Addexbio | One Frozen vial | EUR 543 |
 WIL2-S cells |
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| C0003018 | Addexbio | One Frozen vial | EUR 485 |
 SUP-B15 cells |
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| C0003019 | Addexbio | One Frozen vial | EUR 485 |
 THP-1 cells |
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| C0003024 | Addexbio | One Frozen vial | EUR 455 |
 MV4:11 cells |
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| C0003025 | Addexbio | One Frozen vial | EUR 455 |
 NALM-6 cells |
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| C0003030 | Addexbio | One Frozen vial | EUR 485 |
 SJSA-1 cells |
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| C0004004 | Addexbio | One Frozen vial | EUR 520 |
 LN-319 cells |
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| C0005001 | Addexbio | One Frozen vial | EUR 777 |
 SH-Sy5y cells |
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| C0005004 | Addexbio | One Frozen vial | EUR 455 |
 SF-295 cells |
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| C0005005 | Addexbio | One Frozen vial | EUR 485 |
 A-172 cells |
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| C0005009 | Addexbio | One Frozen vial | EUR 455 |
 U-251MG cells |
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| C0005029 | Addexbio | One Frozen vial | EUR 777 |
 bEnd.3 cells |
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| C0005030 | Addexbio | One Frozen vial | EUR 467 |
 JIMT-1 cells |
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| C0006005 | Addexbio | One Frozen vial | EUR 543 |
 MCF-7 cells |
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| C0006008 | Addexbio | One Frozen vial | EUR 455 |
 AU-565 cells |
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| C0006010 | Addexbio | One Frozen vial | EUR 455 |
 BT-474 cells |
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| C0006012 | Addexbio | One Frozen vial | EUR 455 |
 BT-483 cells |
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| C0006013 | Addexbio | One Frozen vial | EUR 485 |
 BT-20 cells |
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| C0006014 | Addexbio | One Frozen vial | EUR 455 |
 BT-549 cells |
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| C0006017 | Addexbio | One Frozen vial | EUR 485 |
 Hep-2C cells |
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| C0008008 | Addexbio | One Frozen vial | EUR 543 |
 HCA-7 cells |
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| C0009003 | Addexbio | One Frozen vial | EUR 777 |
 HT-29 cells |
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| C0009004 | Addexbio | One Frozen vial | EUR 455 |
 HCT-116 cells |
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| C0009005 | Addexbio | One Frozen vial | EUR 455 |
 LS-180 cells |
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| C0009006 | Addexbio | One Frozen vial | EUR 455 |
 DLD-1 cells |
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| C0009007 | Addexbio | One Frozen vial | EUR 455 |
 Caco-2 cells |
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| C0009009 | Addexbio | One Frozen vial | EUR 455 |
The concentrations of 17β-estradiol (E2) and testosterone (T) were determined using commercially available ELISA kits. The results indicate the administration of GnRHa had marked effects on reductions of morphological deformities in the offspring and promoted development during the larval stage by inducing sexual maturity in both treated parents. The E2/T ratio results indicate the presence of endocrine disruptors.
It is concluded that the use of GnRHa at a dose of 10 ug/kg in captive male and female Atlantic salmon broodstock has an inhibitory effect on the impacts of endocrine disruptors, does not affect fertilization rate, and has positive effects on development of offspring by reducing the number of morphological deformities during the larval stage of development.