GnRHa treatments of Atlantic Salmon broodstock suppresses effects of endocrine disruptors, benefitting offspring quality.

The use of synthetic hormones to regulate sexual maturity in captive fish is a common practice. With aquaculture practices, fish production is desired throughout the year, necessitating the maintenance of quality standards, mainly regarding the characteristics of the fish produced.

Embryonic development may be affected by toxins in the environment and by a variety of pathologies. The aim of this study was to determine the effects of treatment with gonadotropin-releasing hormone analog (GnRHa) on captive male and female Atlantic Salmon (Salmo salar) broodstock, observing the effects on the hormonal milieu and impacts on breeding outcomes. Sexually mature fish were fertilized with and without imposing a GnRHa treatment to evaluate the development of offspring up to the fry stage.

5637 cells

C0002001 One Frozen vial
EUR 582

MB49 cells

C0002004 One Frozen vial
EUR 932.4

K562 cells

C0003004 One Frozen vial
EUR 546

U937 cells

C0003005 One Frozen vial
EUR 546

Raji cells

C0003009 One Frozen vial
EUR 546

Daudi cells

C0003010 One Frozen vial
EUR 546

RS4;11 cells

C0003012 One Frozen vial
EUR 546

NAMALWA cells

C0003013 One Frozen vial
EUR 546

BJAB cells

C0003016 One Frozen vial
EUR 651.6

FO cells

C0003017 One Frozen vial
EUR 582

MC116 cells

C0003021 One Frozen vial
EUR 582

P3X63Ag8.653 cells

C0003028 One Frozen vial
EUR 546

REH cells

C0003031 One Frozen vial
EUR 582

Mino cells

C0003033 One Frozen vial
EUR 582

U87MG cells

C0005002 One Frozen vial
EUR 546

B103 cells

C0005003 One Frozen vial
EUR 932.4

T47D cells

C0006001 One Frozen vial
EUR 546

4T1 cells

C0006004 One Frozen vial
EUR 546

HeLa cells

C0008001 One Frozen vial
EUR 546

SiHa cells

C0008002 One Frozen vial
EUR 546

C33A cells

C0008003 One Frozen vial
EUR 546

CaSKi cells

C0008004 One Frozen vial
EUR 546

SW480 cells

C0009001 One Frozen vial
EUR 546

SW620 cells

C0009002 One Frozen vial
EUR 546

T84 cells

C0009008 One Frozen vial
EUR 546

HCT15 cells

C0009010 One Frozen vial
EUR 546

LoVo cells

C0009011 One Frozen vial
EUR 546

RKO cells

C0009012 One Frozen vial
EUR 546

SW48 cells

C0009014 One Frozen vial
EUR 546

SW1116 cells

C0009019 One Frozen vial
EUR 546

H716 cells

C0009022 One Frozen vial
EUR 651.6

OE33 cells

C0013003 One Frozen vial
EUR 792

JROECL33 cells

C0013004 One Frozen vial
EUR 792

Hep3B cells

C0015001 One Frozen vial
EUR 546

HepG2 cells

C0015002 One Frozen vial
EUR 546

Calu3 cells

C0016001 One Frozen vial
EUR 546

A549 cells

C0016002 One Frozen vial
EUR 546

H460 cells

C0016003 One Frozen vial
EUR 546

A427 cells

C0016004 One Frozen vial
EUR 546

H23 cells

C0016005 One Frozen vial
EUR 546

H1703 cells

C0016008 One Frozen vial
EUR 651.6

SW1573 cells

C0016009 One Frozen vial
EUR 651.6

H520 cells

C0016010 One Frozen vial
EUR 546

H226 cells

C0016011 One Frozen vial
EUR 546

HCC4006 cells

C0016012 One Frozen vial
EUR 546

H1975 cells

C0016013 One Frozen vial
EUR 651.6

H1650 cells

C0016015 One Frozen vial
EUR 651.6

H358 cells

C0016016 One Frozen vial
EUR 546

H2228 cells

C0016017 One Frozen vial
EUR 651.6

H2170 cells

C0016018 One Frozen vial
EUR 546

H441 cells

C0016019 One Frozen vial
EUR 546

H596 cells

C0016020 One Frozen vial
EUR 546

H1581 cells

C0016028 One Frozen vial
EUR 651.6

H2444 cells

C0016038 One Frozen vial
EUR 651.6

H69AR cells

C0016046 One Frozen vial
EUR 651.6

H1373 cells

C0016047 One Frozen vial
EUR 651.6

H2122 cells

C0016048 One Frozen vial
EUR 651.6

H526 cells

C0016052 One Frozen vial
EUR 546

H1299 cells

C0016053 One Frozen vial
EUR 546

H446 cells

C0016054 One Frozen vial
EUR 651.6

H1770 cells

C0016057 One Frozen vial
EUR 651.6

H1184 cells

C0016058 One Frozen vial
EUR 651.6

H1694 cells

C0016060 One Frozen vial
EUR 651.6

H187 cells

C0016061 One Frozen vial
EUR 546

H1963 cells

C0016062 One Frozen vial
EUR 651.6

H209 cells

C0016063 One Frozen vial
EUR 546

H69 cells

C0016065 One Frozen vial
EUR 546

H82 cells

C0016066 One Frozen vial
EUR 546

H847 cells

C0016067 One Frozen vial
EUR 651.6

H660 cells

C0016068 One Frozen vial
EUR 834

SW1271 cells

C0016073 One Frozen vial
EUR 651.6

A673 cells

C0016074 One Frozen vial
EUR 546

H524 cells

C0016077 One Frozen vial
EUR 651.6

H211 cells

C0016078 One Frozen vial
EUR 651.6

H146 cells

C0016080 One Frozen vial
EUR 546

H889 cells

C0016081 One Frozen vial
EUR 651.6

H510A cells

C0016082 One Frozen vial
EUR 546

H128 cells

C0016083 One Frozen vial
EUR 651.6

H1048 cells

C0016084 One Frozen vial
EUR 651.6

A2780 cells

C0017002 One Frozen vial
EUR 651.6

A2780cis cells

C0017003 One Frozen vial
EUR 722.4

E3LZ10.7 cells

C0018005 One Frozen vial
EUR 792

A10.7 cells

C0018006 One Frozen vial
EUR 792

Vcap cells

C0019001 One Frozen vial
EUR 546

C32 cells

C0020002 One Frozen vial
EUR 546

N87 cells

C0023002 One Frozen vial
EUR 546

AGS cells

C0023004 One Frozen vial
EUR 546

8505C cells

C0025002 One Frozen vial
EUR 792

K1 cells

C0025003 One Frozen vial
EUR 792

R2C cells

C0028001 One Frozen vial
EUR 651.6

Y79 cells

C0029001 One Frozen vial
EUR 546

BeWo cells

C0030001 One Frozen vial
EUR 546

T11D7e2 cells

C0033001 One Frozen vial
EUR 722.4

NB3 cells

C0033003 One Frozen vial
EUR 792

RD cells

C0035001 One Frozen vial
EUR 546

MDCKII cells

P0014001 One Frozen vial
EUR 546

VERO cells

P0014002 One Frozen vial
EUR 546

MDCK cells

P0014003 One Frozen vial
EUR 546

BJ cells

P0020005 One Frozen vial
EUR 546

HUVEC cells

P0027001 One Frozen vial
EUR 582

C2C12 cells

P0028001 One Frozen vial
EUR 546

ST cells

P0028002 One Frozen vial
EUR 651.6

HASM cells

P0001001 One Frozen vial
EUR 932.4

HBSM cells

P0007001 One Frozen vial
EUR 932.4

SCBN cells

P0010001 One Frozen vial
EUR 651.6

STO cells

P0011006 One Frozen vial
EUR 546

A9 cells

P0011007 One Frozen vial
EUR 651.6

L929 cells

P0011012 One Frozen vial
EUR 546

C127 cells

S0006001 One Frozen vial
EUR 582

hFOB1.19 cells

T0004005 One Frozen vial
EUR 546

SVGp12 cells

T0005008 One Frozen vial
EUR 651.6

BSC40 cells

T0011003 One Frozen vial
EUR 651.6

Mv1Lu cells

T0016003 One Frozen vial
EUR 546

IMCC3 cells

T0017001 One Frozen vial
EUR 862.8

HPDEC cells

T0018001 One Frozen vial
EUR 932.4

HaCaT cells

T0020001 One Frozen vial
EUR 862.8

Hs27 cells

T0020010 One Frozen vial
EUR 546

TM3 cells

T0028002 One Frozen vial
EUR 546

Neural Stem Cells (iPSC from Blood Cells; Male)

ASE-9234 1 vial (1 x 10^6)
EUR 497.4
Description: 12 month

Neural Stem Cells (iPSC from Blood Cells; Female)

ASE-9234F 1 vial (1 x 10^6)
EUR 497.4
Description: 12 month

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-10 Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-20 Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-30 Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-40 Ask for price

Human Cord Blood CD34+ Cells Derived Endothelial Cells

HEC23 500,000+ Cells
EUR 1296

MEF Feeder Cells

CBA-310 1 vial
EUR 470.4
Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells.

JK1 Feeder Cells

CBA-315 1 vial
EUR 922.8
Description: JK1 Feeder Cells are used for the maintenance of numerous types of stem cells in their undifferentiated state.  The cells must be mitotically inactivated prior to the addition of ES cells, such as treatment with mitomycin C (2-4 hr, 10 µg/mL).

SNL Feeder Cells

CBA-316 1 vial
EUR 922.8
Description: The SNL 76/7 cell line, established by Dr. Allan Bradley, is clonally derived from a mouse fibroblast STO cell line transformed with neomycin resistance and murine LIF genes. SNL can be used as a feeder cell for ES cell growth, and it also has been recently used in mouse or human iPS culture.

CCRF-CEM cells

C0003001 One Frozen vial
EUR 546

RPMI-8226 cells

C0003002 One Frozen vial
EUR 546

MOLM-13 cells

C0003003 One Frozen vial
EUR 651.6

LP-1 cells

C0003006 One Frozen vial
EUR 651.6

PBL-2H3 cells

C0003007 One Frozen vial
EUR 546

RAW 264.7 cells

C0003008 One Frozen vial
EUR 546

F-36P cells

C0003014 One Frozen vial
EUR 651.6

SD-1 cells

C0003015 One Frozen vial
EUR 651.6

WIL2-S cells

C0003018 One Frozen vial
EUR 582

SUP-B15 cells

C0003019 One Frozen vial
EUR 582

THP-1 cells

C0003024 One Frozen vial
EUR 546

MV4:11 cells

C0003025 One Frozen vial
EUR 546

NALM-6 cells

C0003030 One Frozen vial
EUR 582

SJSA-1 cells

C0004004 One Frozen vial
EUR 624

LN-319 cells

C0005001 One Frozen vial
EUR 932.4

SH-Sy5y cells

C0005004 One Frozen vial
EUR 546

SF-295 cells

C0005005 One Frozen vial
EUR 582

A-172 cells

C0005009 One Frozen vial
EUR 546

U-251MG cells

C0005029 One Frozen vial
EUR 932.4

bEnd.3 cells

C0005030 One Frozen vial
EUR 560.4

JIMT-1 cells

C0006005 One Frozen vial
EUR 651.6

MCF-7 cells

C0006008 One Frozen vial
EUR 546

AU-565 cells

C0006010 One Frozen vial
EUR 546

BT-474 cells

C0006012 One Frozen vial
EUR 546

BT-483 cells

C0006013 One Frozen vial
EUR 582

BT-20 cells

C0006014 One Frozen vial
EUR 546

BT-549 cells

C0006017 One Frozen vial
EUR 582

Hep-2C cells

C0008008 One Frozen vial
EUR 651.6

HCA-7 cells

C0009003 One Frozen vial
EUR 932.4

HT-29 cells

C0009004 One Frozen vial
EUR 546

HCT-116 cells

C0009005 One Frozen vial
EUR 546

LS-180 cells

C0009006 One Frozen vial
EUR 546

DLD-1 cells

C0009007 One Frozen vial
EUR 546

Caco-2 cells

C0009009 One Frozen vial
EUR 546

LS-174T cells

C0009013 One Frozen vial
EUR 546

SNU-503 cells

C0009015 One Frozen vial
EUR 609.6

SNU-407 cells

C0009016 One Frozen vial
EUR 582

The concentrations of 17β-estradiol (E2) and testosterone (T) were determined using commercially available ELISA kits. The results indicate the administration of GnRHa had marked effects on reductions of morphological deformities in the offspring and promoted development during the larval stage by inducing sexual maturity in both treated parents. The E2/T ratio results indicate the presence of endocrine disruptors.

It is concluded that the use of GnRHa at a dose of 10 ug/kg in captive male and female Atlantic salmon broodstock has an inhibitory effect on the impacts of endocrine disruptors, does not affect fertilization rate, and has positive effects on development of offspring by reducing the number of morphological deformities during the larval stage of development.