GnRHa treatments of Atlantic Salmon broodstock suppresses effects of endocrine disruptors, benefitting offspring quality.

The use of synthetic hormones to regulate sexual maturity in captive fish is a common practice. With aquaculture practices, fish production is desired throughout the year, necessitating the maintenance of quality standards, mainly regarding the characteristics of the fish produced.

Embryonic development may be affected by toxins in the environment and by a variety of pathologies. The aim of this study was to determine the effects of treatment with gonadotropin-releasing hormone analog (GnRHa) on captive male and female Atlantic Salmon (Salmo salar) broodstock, observing the effects on the hormonal milieu and impacts on breeding outcomes. Sexually mature fish were fertilized with and without imposing a GnRHa treatment to evaluate the development of offspring up to the fry stage.

C127 cells

S0006001 One Frozen vial
EUR 485

HASM cells

P0001001 One Frozen vial
EUR 777

HBSM cells

P0007001 One Frozen vial
EUR 777

SCBN cells

P0010001 One Frozen vial
EUR 543

STO cells

P0011006 One Frozen vial
EUR 455

A9 cells

P0011007 One Frozen vial
EUR 543

L929 cells

P0011012 One Frozen vial
EUR 455

MDCKII cells

P0014001 One Frozen vial
EUR 455

VERO cells

P0014002 One Frozen vial
EUR 455

MDCK cells

P0014003 One Frozen vial
EUR 455

BJ cells

P0020005 One Frozen vial
EUR 455

HUVEC cells

P0027001 One Frozen vial
EUR 485

C2C12 cells

P0028001 One Frozen vial
EUR 455

ST cells

P0028002 One Frozen vial
EUR 543

hFOB1.19 cells

T0004005 One Frozen vial
EUR 455

SVGp12 cells

T0005008 One Frozen vial
EUR 543

BSC40 cells

T0011003 One Frozen vial
EUR 543

Mv1Lu cells

T0016003 One Frozen vial
EUR 455

IMCC3 cells

T0017001 One Frozen vial
EUR 719

HPDEC cells

T0018001 One Frozen vial
EUR 777

HaCaT cells

T0020001 One Frozen vial
EUR 719

Hs27 cells

T0020010 One Frozen vial
EUR 455

TM3 cells

T0028002 One Frozen vial
EUR 455

5637 cells

C0002001 One Frozen vial
EUR 485

MB49 cells

C0002004 One Frozen vial
EUR 777

K562 cells

C0003004 One Frozen vial
EUR 455

U937 cells

C0003005 One Frozen vial
EUR 455

Raji cells

C0003009 One Frozen vial
EUR 455

Daudi cells

C0003010 One Frozen vial
EUR 455

RS4;11 cells

C0003012 One Frozen vial
EUR 455

NAMALWA cells

C0003013 One Frozen vial
EUR 455

BJAB cells

C0003016 One Frozen vial
EUR 543

FO cells

C0003017 One Frozen vial
EUR 485

MC116 cells

C0003021 One Frozen vial
EUR 485

P3X63Ag8.653 cells

C0003028 One Frozen vial
EUR 455

REH cells

C0003031 One Frozen vial
EUR 485

Mino cells

C0003033 One Frozen vial
EUR 485

U87MG cells

C0005002 One Frozen vial
EUR 455

B103 cells

C0005003 One Frozen vial
EUR 777

T47D cells

C0006001 One Frozen vial
EUR 455

4T1 cells

C0006004 One Frozen vial
EUR 455

HeLa cells

C0008001 One Frozen vial
EUR 455

SiHa cells

C0008002 One Frozen vial
EUR 455

C33A cells

C0008003 One Frozen vial
EUR 455

CaSKi cells

C0008004 One Frozen vial
EUR 455

SW480 cells

C0009001 One Frozen vial
EUR 455

SW620 cells

C0009002 One Frozen vial
EUR 455

T84 cells

C0009008 One Frozen vial
EUR 455

HCT15 cells

C0009010 One Frozen vial
EUR 455

LoVo cells

C0009011 One Frozen vial
EUR 455

RKO cells

C0009012 One Frozen vial
EUR 455

SW48 cells

C0009014 One Frozen vial
EUR 455

SW1116 cells

C0009019 One Frozen vial
EUR 455

H716 cells

C0009022 One Frozen vial
EUR 543

OE33 cells

C0013003 One Frozen vial
EUR 660

JROECL33 cells

C0013004 One Frozen vial
EUR 660

Hep3B cells

C0015001 One Frozen vial
EUR 455

HepG2 cells

C0015002 One Frozen vial
EUR 455

Calu3 cells

C0016001 One Frozen vial
EUR 455

A549 cells

C0016002 One Frozen vial
EUR 455

H460 cells

C0016003 One Frozen vial
EUR 455

A427 cells

C0016004 One Frozen vial
EUR 455

H23 cells

C0016005 One Frozen vial
EUR 455

H1703 cells

C0016008 One Frozen vial
EUR 543

SW1573 cells

C0016009 One Frozen vial
EUR 543

H520 cells

C0016010 One Frozen vial
EUR 455

H226 cells

C0016011 One Frozen vial
EUR 455

HCC4006 cells

C0016012 One Frozen vial
EUR 455

H1975 cells

C0016013 One Frozen vial
EUR 543

H1650 cells

C0016015 One Frozen vial
EUR 543

H358 cells

C0016016 One Frozen vial
EUR 455

H2228 cells

C0016017 One Frozen vial
EUR 543

H2170 cells

C0016018 One Frozen vial
EUR 455

H441 cells

C0016019 One Frozen vial
EUR 455

H596 cells

C0016020 One Frozen vial
EUR 455

H1581 cells

C0016028 One Frozen vial
EUR 543

H2444 cells

C0016038 One Frozen vial
EUR 543

H69AR cells

C0016046 One Frozen vial
EUR 543

H1373 cells

C0016047 One Frozen vial
EUR 543

H2122 cells

C0016048 One Frozen vial
EUR 543

H526 cells

C0016052 One Frozen vial
EUR 455

H1299 cells

C0016053 One Frozen vial
EUR 455

H446 cells

C0016054 One Frozen vial
EUR 543

H1770 cells

C0016057 One Frozen vial
EUR 543

H1184 cells

C0016058 One Frozen vial
EUR 543

H1694 cells

C0016060 One Frozen vial
EUR 543

H187 cells

C0016061 One Frozen vial
EUR 455

H1963 cells

C0016062 One Frozen vial
EUR 543

H209 cells

C0016063 One Frozen vial
EUR 455

H69 cells

C0016065 One Frozen vial
EUR 455

H82 cells

C0016066 One Frozen vial
EUR 455

H847 cells

C0016067 One Frozen vial
EUR 543

H660 cells

C0016068 One Frozen vial
EUR 695

SW1271 cells

C0016073 One Frozen vial
EUR 543

A673 cells

C0016074 One Frozen vial
EUR 455

H524 cells

C0016077 One Frozen vial
EUR 543

H211 cells

C0016078 One Frozen vial
EUR 543

H146 cells

C0016080 One Frozen vial
EUR 455

H889 cells

C0016081 One Frozen vial
EUR 543

H510A cells

C0016082 One Frozen vial
EUR 455

H128 cells

C0016083 One Frozen vial
EUR 543

H1048 cells

C0016084 One Frozen vial
EUR 543

A2780 cells

C0017002 One Frozen vial
EUR 543

A2780cis cells

C0017003 One Frozen vial
EUR 602

E3LZ10.7 cells

C0018005 One Frozen vial
EUR 660

A10.7 cells

C0018006 One Frozen vial
EUR 660

Vcap cells

C0019001 One Frozen vial
EUR 455

C32 cells

C0020002 One Frozen vial
EUR 455

N87 cells

C0023002 One Frozen vial
EUR 455

AGS cells

C0023004 One Frozen vial
EUR 455

8505C cells

C0025002 One Frozen vial
EUR 660

K1 cells

C0025003 One Frozen vial
EUR 660

R2C cells

C0028001 One Frozen vial
EUR 543

Y79 cells

C0029001 One Frozen vial
EUR 455

BeWo cells

C0030001 One Frozen vial
EUR 455

T11D7e2 cells

C0033001 One Frozen vial
EUR 602

NB3 cells

C0033003 One Frozen vial
EUR 660

RD cells

C0035001 One Frozen vial
EUR 455

Human Cord Blood CD34+ Cells Derived Endothelial Cells

HEC23 500,000+ Cells
EUR 1080

Neural Stem Cells (iPSC from Blood Cells; Male)

ASE-9234 1 vial (1 x 10^6)
EUR 414.5
Description: 12 month

Neural Stem Cells (iPSC from Blood Cells; Female)

ASE-9234F 1 vial (1 x 10^6)
EUR 414.5
Description: 12 month

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-10 Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-20 Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-30 Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-40 Ask for price

L-WRN cells

S0011002 One Frozen vial
EUR 543

HEK-CaSR cells

S0014002 One Frozen vial
EUR 1011

CHO-hNCX1 cells

S0017001 One Frozen vial
EUR 1011

CHO-hTRPV1 cells

S0017002 One Frozen vial
EUR 1011

LacZ stable cells

SC003 2 x 106 cell/ml x 1ml
EUR 2225
Description: LacZ (β-Galactosidase) stable cell line in HEK293 cell line with Blasticidin resistance

TAT stable cells

SC012 2 x 106 cell/ml x 1ml
EUR 1500
Description: Stable cell line expressing codon humanized TAT gene and RFP with Blasticidin resistance

CTX TNA2 cells

P0005006 One Frozen vial
EUR 543

NIH-3T3 cells

P0011001 One Frozen vial
EUR 455

3T3-L1 cells

P0011002 One Frozen vial
EUR 455

3T3-J2 cells

P0011008 One Frozen vial
EUR 426

LLC-MK2 cells

P0014004 One Frozen vial
EUR 543

CHO-K1 cells

P0017001 One Frozen vial
EUR 455

IEC-6 cells

P0021001 One Frozen vial
EUR 455

HBEC-5i cells

T0005011 One Frozen vial
EUR 543

BEAS-2B cells

T0007001 One Frozen vial
EUR 455

HEK-293 cells

T0011001 One Frozen vial
EUR 455

HEK-293T cells

T0011002 One Frozen vial
EUR 455

HK-2 cells

T0011004 One Frozen vial
EUR 455

NE-1 cells

T0013001 One Frozen vial
EUR 777

COS-1 cells

T0014001 One Frozen vial
EUR 455

COS-7 cells

T0014002 One Frozen vial
EUR 455

THLE-2 cells

T0015001 One Frozen vial
EUR 455

THLE-3 cells

T0015002 One Frozen vial
EUR 455

3D4/2 cells

T0016001 One Frozen vial
EUR 543

MRC-5 cells

T0016002 One Frozen vial
EUR 455

WI-38 cells

T0016037 One Frozen vial
EUR 455

HEL 299 cells

T0016051 One Frozen vial
EUR 455

Cortical Astroglial Cells

PC36108 Cortical Pair from E18 Rat
EUR 396

Hippocampal Astroglial Cells

PC36109 Hippocampal Pair from E18 Rat
EUR 396

Human Schwann Cells

HMP303 500,000 Cells - Frozen
EUR 1184

MEF Feeder Cells

CBA-310 1 vial
EUR 392
Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells.

JK1 Feeder Cells

CBA-315 1 vial
EUR 769
Description: JK1 Feeder Cells are used for the maintenance of numerous types of stem cells in their undifferentiated state.  The cells must be mitotically inactivated prior to the addition of ES cells, such as treatment with mitomycin C (2-4 hr, 10 µg/mL).

SNL Feeder Cells

CBA-316 1 vial
EUR 769
Description: The SNL 76/7 cell line, established by Dr. Allan Bradley, is clonally derived from a mouse fibroblast STO cell line transformed with neomycin resistance and murine LIF genes. SNL can be used as a feeder cell for ES cell growth, and it also has been recently used in mouse or human iPS culture.

CCRF-CEM cells

C0003001 One Frozen vial
EUR 455

RPMI-8226 cells

C0003002 One Frozen vial
EUR 455

MOLM-13 cells

C0003003 One Frozen vial
EUR 543

LP-1 cells

C0003006 One Frozen vial
EUR 543

PBL-2H3 cells

C0003007 One Frozen vial
EUR 455

RAW 264.7 cells

C0003008 One Frozen vial
EUR 455

F-36P cells

C0003014 One Frozen vial
EUR 543

The concentrations of 17β-estradiol (E2) and testosterone (T) were determined using commercially available ELISA kits. The results indicate the administration of GnRHa had marked effects on reductions of morphological deformities in the offspring and promoted development during the larval stage by inducing sexual maturity in both treated parents. The E2/T ratio results indicate the presence of endocrine disruptors.

It is concluded that the use of GnRHa at a dose of 10 ug/kg in captive male and female Atlantic salmon broodstock has an inhibitory effect on the impacts of endocrine disruptors, does not affect fertilization rate, and has positive effects on development of offspring by reducing the number of morphological deformities during the larval stage of development.