The aim of this study was to estimate the levels of circulating carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in subjects with gestational diabetes mellitus (GDM) and investigate the relationships between CEACAM1 and GDM. Circulating CEACAM1 levels were measured by ELISA kit in 70 women with GDM and 70 normal glucose tolerance (NGT) pregnant women. Blood samples were collected to detect fasting plasma glucose (FPG), fasting insulin (FINS) and glycosylated hemoglobin (HbA1c) levels in all participants. Insulin sensitivity index (ISOGTT) was calculated to assess insulin sensitivity.
Correlation analysis was performed between serum CEACAM1 levels and other parameters.Circulating CEACAM1 levels were higher in the GDM group than that in the NGT pregnant group, however, the difference showed no statistical significance (1889.82 ± 616.14 vs 1758.92 ± 433.15 pg/ml, p > 0.05). In GDM group, CEACAM1 was positively correlated with ISOGTT (R = 0.39, P = 0.001), while negatively with 1 h post-meal plasma insulin level (1hPINS) (R = -0.32, P = 0.008), 2 h post-meal plasma insulin level (2hPINS) (R = -0.33, P = 0.006) and area under curve of insulin (AUCI) (R = -0.36, P = 0.002) when adjusting for maternal age and gestational age.
The present study showed that circulating CEACAM1 levels did not differ in both GDM and NGT groups. However, we found a significant positively correlation between CEACAM1 and insulin sensitivity in the GDM group.
DACH1, a novel target of miR-218, participates in the regulation of cell viability, apoptosis, inflammatory response, and epithelial-mesenchymal transition process in renal tubule cells treated by high-glucose.
Objective: This report was designed to assess the functional role of miR-218/dachshund family transcription factor 1 (DACH1) in diabetic kidney disease (DKD) and investigate its possible molecular mechanism.Materials and Methods: From the GEO database, we downloaded different datasets for analyzing the expression of miR-218 and DACH1 in DKD. TargetScan was adopted to predict the binding sites between miR-218 and DACH1, which was further verified by dual-luciferase reporter assays. The renal proximal tubule cells (HK-2) treated with high glucose (HG) were used as an in vitro model.
QRT-PCR and western blot were used to determine the expression of DACH1 and other relative factors. Cell counting kit-8 and flow cytometer were applied to detect cell viability and apoptosis. The levels of inflammatory cytokines were determined by an ELISA assay.
NKG2D antibody (biotin) |
61R-1605 |
Fitzgerald |
100 ug |
EUR 418.8 |
Description: Armenian Hamster monoclonal NKG2D antibody (biotin) |
NKG2D antibody (allophycocyanin) |
61R-1778 |
Fitzgerald |
100 ug |
EUR 573.6 |
Description: Rat monoclonal NKG2D antibody (allophycocyanin) |
CD314 (NKG2D) Antibody |
abx201090-01mg |
Abbexa |
0.1 mg |
EUR 477.6 |
|
CD314 (NKG2D) |
314A-100T |
ImmunoStep |
100 test |
EUR 730.8 |
CD314 (NKG2D) |
314B-01MG |
ImmunoStep |
0,1 mg |
EUR 340.8 |
CD314 (NKG2D) |
314F-100T |
ImmunoStep |
100 test |
EUR 450 |
CD314 (NKG2D) |
314PE-100T |
ImmunoStep |
100 test |
EUR 840 |
CD314 (NKG2D) |
314PU-01MG |
ImmunoStep |
0,1 mg |
EUR 356.4 |
CD314 (NKG2D) |
MO314PE(V50) |
ImmunoStep |
50 ug |
EUR 60 |
NKG2D Polyclonal Conjugated Antibody |
C46825 |
SAB |
100ul |
EUR 476.4 |
CD314 (NKG2D) Antibody (FITC) |
abx201091-100tests |
Abbexa |
100 tests |
EUR 560.4 |
|
CD314 (NKG2D) Antibody (PE) |
abx201092-100tests |
Abbexa |
100 tests |
EUR 927.6 |
|
CD314 (NKG2D) Antibody (APC) |
abx201093-100tests |
Abbexa |
100 tests |
EUR 828 |
|
CD314 (NKG2D) Antibody (Biotin) |
abx201094-01mg |
Abbexa |
0.1 mg |
EUR 460.8 |
|
Anti-NKG2D/KLRK1 Antibody |
A00661-1 |
BosterBio |
100ug/vial |
EUR 352.8 |
NKG2D Ligand 2 (ULBP2) Antibody |
20-abx142298 |
Abbexa |
-
EUR 444.00
-
EUR 727.20
-
EUR 376.80
|
|
|
NKG2D Ligand 2 (ULBP2) Antibody |
20-abx005773 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
NKG2D Ligand 2 (ULBP2) Antibody |
abx029272-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
NKG2D Ligand 2 (ULBP2) Antibody |
abx029272-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
NKG2D Ligand 2 (ULBP2) Antibody |
20-abx320552 |
Abbexa |
|
|
|
NKG2D Ligand 2 (ULBP2) Antibody |
abx239250-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
NKG2D / CD314 Recombinant Protein |
11-282 |
ProSci |
0.1 mg |
EUR 651.3 |
Description: NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors, also known as KLRK1, CD314, D12S2489E, KLR and killer cell lectin like receptor K1. NKG2D itself forms a homodimer whose ectodomains serve for ligand binding. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. In NK cells, NKG2D serves as an activating receptor, which itself is able to trigger cytotoxicity. The function of NKG2D on CD8+ T cells is to send co-stimulatory signals to activate them. |
NKG2D / CD314 Recombinant Protein |
11-299 |
ProSci |
0.1 mg |
EUR 651.3 |
Description: NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors, also known as KLRK1, CD314, D12S2489E, KLR and killer cell lectin like receptor K1. NKG2D itself forms a homodimer whose ectodomains serve for ligand binding. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. In NK cells, NKG2D serves as an activating receptor, which itself is able to trigger cytotoxicity. The function of NKG2D on CD8+ T cells is to send co-stimulatory signals to activate them. |
NKG2D / CD314 Recombinant Protein |
11-223 |
ProSci |
0.1 mg |
EUR 651.3 |
Description: NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors, also known as KLRK1, CD314, D12S2489E, KLR and killer cell lectin like receptor K1. NKG2D itself forms a homodimer whose ectodomains serve for ligand binding. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. In NK cells, NKG2D serves as an activating receptor, which itself is able to trigger cytotoxicity. The function of NKG2D on CD8+ T cells is to send co-stimulatory signals to activate them. |
Polyclonal Goat Anti-NKG2D / KLRK1 Antibody |
APG00220G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-NKG2D / KLRK1 . This antibody is tested and proven to work in the following applications: |
Human soluble NKG2D ligands ELISA kit |
E01N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human soluble NKG2D ligands ELISA kit |
E01N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human soluble NKG2D ligands ELISA kit |
E01N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat soluble NKG2D ligands ELISA kit |
E06N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat soluble NKG2D ligands ELISA kit |
E06N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat soluble NKG2D ligands ELISA kit |
E06N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog soluble NKG2D ligands ELISA kit |
E08N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog soluble NKG2D ligands ELISA kit |
E08N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog soluble NKG2D ligands ELISA kit |
E08N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat soluble NKG2D ligands ELISA kit |
E02N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat soluble NKG2D ligands ELISA kit |
E02N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat soluble NKG2D ligands ELISA kit |
E02N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse soluble NKG2D ligands ELISA kit |
E03N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse soluble NKG2D ligands ELISA kit |
E03N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse soluble NKG2D ligands ELISA kit |
E03N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit soluble NKG2D ligands ELISA kit |
E04N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit soluble NKG2D ligands ELISA kit |
E04N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit soluble NKG2D ligands ELISA kit |
E04N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig soluble NKG2D ligands ELISA kit |
E07N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Porcine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig soluble NKG2D ligands ELISA kit |
E07N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig soluble NKG2D ligands ELISA kit |
E07N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey soluble NKG2D ligands ELISA kit |
E09N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey soluble NKG2D ligands ELISA kit |
E09N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey soluble NKG2D ligands ELISA kit |
E09N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Recombinant Human NKG2D/CD314/KLRK1 Protein |
RP00417 |
Abclonal |
10 μg |
EUR 208.8 |
Armenian Hamster Anti-Mouse NKG2D Monoclonal antibody, clone HMG2D |
CABT-L4409-1mg |
Creative Diagnostics |
1 mg |
EUR 1076.4 |
Armenian Hamster Anti-Mouse NKG2D Monoclonal antibody, clone HMG2D |
CABT-L4409-5mg |
Creative Diagnostics |
5 mg |
EUR 2886 |
NKG2-D Type II Integral Membrane Protein (NKG2D) Antibody |
abx430571-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Human NKG2D ligand 4(RAET1E) ELISA kit |
CSB-EL019277HU-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 4 (RAET1E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human NKG2D ligand 4(RAET1E) ELISA kit |
1-CSB-EL019277HU |
Cusabio |
-
EUR 964.80
-
EUR 6118.80
-
EUR 3244.80
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 4(RAET1E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human NKG2D ligand 3(ULBP3) ELISA kit |
CSB-EL025611HU-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 3 (ULBP3) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human NKG2D ligand 3(ULBP3) ELISA kit |
1-CSB-EL025611HU |
Cusabio |
-
EUR 964.80
-
EUR 6118.80
-
EUR 3244.80
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 3(ULBP3) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Guinea pig soluble NKG2D ligands ELISA kit |
E05N0038-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig soluble NKG2D ligands ELISA kit |
E05N0038-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig soluble NKG2D ligands ELISA kit |
E05N0038-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
ELISA kit for Human NKG2D ligand 2 |
EK4447 |
SAB |
96 tests |
EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human NKG2D ligand 2 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human ULBP2(NKG2D ligand 2) ELISA Kit |
EH2185 |
FN Test |
96T |
EUR 681.12 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 7.5IU/ml |
Human NKG2D ligand 2 (ULBP2) ELISA Kit |
abx251525-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Human ULBP2/ NKG2D ligand 2 ELISA Kit |
E2641Hu |
Sunlong |
1 Kit |
EUR 685.2 |
ELISA kit for Human NKG2D ligand 4 (RAET1E) |
KTE60982-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 4 (RAET1E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human NKG2D ligand 4 (RAET1E) |
KTE60982-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 4 (RAET1E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human NKG2D ligand 4 (RAET1E) |
KTE60982-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 4 (RAET1E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human NKG2D ligand 2 (ULBP2) |
KTE60089-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 2 (ULBP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human NKG2D ligand 2 (ULBP2) |
KTE60089-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 2 (ULBP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human NKG2D ligand 2 (ULBP2) |
KTE60089-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 2 (ULBP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Human NKG2D Protein (Ile 73-Val 216) [Fc] |
VAng-2608Lsx-100g |
Creative Biolabs |
100 µg |
EUR 1050 |
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1) |
Human NKG2D Protein (Ile 73-Val 216) [Fc] |
VAng-2608Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 6592.8 |
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1) |
Human NKG2D Protein (Ile 73-Val 216) [His] |
VAng-2609Lsx-100g |
Creative Biolabs |
100 µg |
EUR 1050 |
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1) |
Human NKG2D Protein (Ile 73-Val 216) [His] |
VAng-2609Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 6592.8 |
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1) |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc) |
CK50-10ug |
Novoprotein |
10ug |
EUR 175.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc) |
CK50-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc) |
CK50-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc) |
CK50-50ug |
Novoprotein |
50ug |
EUR 363.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His) |
CK78-10ug |
Novoprotein |
10ug |
EUR 175.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His) |
CK78-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His) |
CK78-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His) |
CK78-50ug |
Novoprotein |
50ug |
EUR 363.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc) |
CX42-10ug |
Novoprotein |
10ug |
EUR 175.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc) |
CX42-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc) |
CX42-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc) |
CX42-50ug |
Novoprotein |
50ug |
EUR 363.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His) |
C508-10ug |
Novoprotein |
10ug |
EUR 145.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His) |
C508-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His) |
C508-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His) |
C508-50ug |
Novoprotein |
50ug |
EUR 315.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc) |
CU41-10ug |
Novoprotein |
10ug |
EUR 169.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc) |
CU41-1mg |
Novoprotein |
1mg |
EUR 2008.8 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc) |
CU41-500ug |
Novoprotein |
500ug |
EUR 1423.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc) |
CU41-50ug |
Novoprotein |
50ug |
EUR 363.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Human NKG2D Protein (Ile 73-Val 216) [His] (HPLC-verified) |
VAng-2607Lsx-100g |
Creative Biolabs |
100 µg |
EUR 1050 |
Description: Human NKG2D (CD314) protein, His tag, HPLC-verified, was expressed in human 293 cells. (Uniprot ID: P26718-1) |
Human NKG2D Protein (Ile 73-Val 216) [His] (HPLC-verified) |
VAng-2607Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 6592.8 |
Description: Human NKG2D (CD314) protein, His tag, HPLC-verified, was expressed in human 293 cells. (Uniprot ID: P26718-1) |
Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) |
CP46-10ug |
Novoprotein |
10ug |
EUR 175.2 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) |
CP46-1mg |
Novoprotein |
1mg |
EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) |
CP46-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) |
CP46-50ug |
Novoprotein |
50ug |
EUR 363.6 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
ASAP1 antibody Antibody |
DF8746 |
Affbiotech |
200ul |
EUR 420 |
anti- Antibody^Polyclonal antibody control antibody |
LSMab09882 |
Lifescience Market |
100 ug |
EUR 525.6 |
ARHGDIA Antibody / RHOGDI Antibody |
F54788-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 165 |
ARHGDIA Antibody / RHOGDI Antibody |
F54788-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 379 |
Ly1 Antibody Reactive (LYAR) Antibody |
20-abx123734 |
Abbexa |
|
|
|
Anti-Glycolipid Antibody (AGA) Antibody |
20-abx004855 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
20-abx014333 |
Abbexa |
-
EUR 376.80
-
EUR 117.60
-
EUR 477.60
-
EUR 594.00
|
- 100 ug
- 10 ug
- 200 ug
- 300 µg
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
20-abx008109 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
abx033330-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Ly1 Antibody Reactive (LYAR) Antibody |
abx033330-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Anti-Glycolipid Antibody (AGA) Antibody |
abx036399-100ug |
Abbexa |
100 ug |
EUR 469.2 |
|
Anti-Glycolipid Antibody (AGA) Antibody |
abx230204-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
Anti-Glycoprotein Antibody (GP) Antibody |
20-abx319900 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Anti-Glycoprotein Antibody (GP) Antibody |
20-abx319901 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Anti-Glycoprotein Antibody (GP) Antibody |
20-abx319905 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Anti-Glycoprotein Antibody (GP) Antibody |
20-abx319913 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
20-abx311665 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
20-abx324434 |
Abbexa |
|
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
abx234901-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
Anti-Anti-SEPT6 antibody antibody |
STJ11100949 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
Anti-Anti-SEPT9 Antibody antibody |
STJ111369 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
Anti-Anti-SEPT4 Antibody antibody |
STJ112276 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
Anti-Anti-SEPT5 Antibody antibody |
STJ25477 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
Anti-Anti-SEPT8 Antibody antibody |
STJ25479 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Anti-Anti-SEPT7 Antibody antibody |
STJ28963 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
Anti-Anti-SEPT1 antibody antibody |
STJ119580 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
Anti-Anti-SEPT12 Antibody antibody |
STJ117759 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. |
Anti-Anti-SEPT5 Antibody antibody |
STJ114819 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
Anti-Anti-SEPT7 Antibody antibody |
STJ116214 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
Anti-Anti-SEPT8 Antibody antibody |
STJ117206 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
CLCN5 Antibody / CIC-5 antibody |
RQ6462 |
NSJ Bioreagents |
100ug |
EUR 419 |
Description: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. |
Cytokeratin 7 antibody-Cytoskeleton Marker Antibody |
48169-100ul |
SAB |
100ul |
EUR 399.6 |
Cytokeratin 7 antibody-Cytoskeleton Marker Antibody |
48169-50ul |
SAB |
50ul |
EUR 286.8 |
Antibody Pair to ApoA-V antibody |
10R-1876 |
Fitzgerald |
100 ul |
EUR 781.2 |
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody |
Anti CD22 Antibody: CD22 Monoclonal Antibody |
065-A-01mg |
Virogen |
0,1 mg |
EUR 321 |
|
Description: anti-CD22 monoclonal antibody |
Anti CD22 Antibody: CD22 Monoclonal Antibody |
065-A-1000ug |
Virogen |
1000 ug |
EUR 1539 |
|
Description: anti-CD22 monoclonal antibody |
Ly1 Antibody Reactive Homolog (LYAR) Antibody |
20-abx103034 |
Abbexa |
-
EUR 543.60
-
EUR 159.60
-
EUR 1562.40
-
EUR 744.00
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Results: A prominent raise of miR-218 was observed in DKD through bioinformatics analysis, which was further confirmed in the HG-induced model. DACH1 is a target of miR-218. miR-218 reduced cell viability and induced apoptosis by negatively regulating DACH1. Moreover, upregulating miR-218 in HG models increased the concentrations of pro-inflammatory cytokines TNF-α and IL-1β, reduced the level of anti-inflammatory cytokine IL-10, and promoted the epithelial-mesenchymal transition (EMT) process, which is possibly achieved by targeting DACH1.
While downregulating miR-218 showed the opposite results.Conclusion: These data demonstrated that, under an in vitro HG environment, miR-218 suppressed the HK-2 cells proliferation, promoted apoptosis, caused an inflammatory response, and facilitated the EMT process largely by targeting DACH1, providing an insight into the therapeutic intervention of DKD.