Association of circulating CEACAM1 levels and insulin sensitivity in gestational diabetes mellitus.

The aim of this study was to estimate the levels of circulating carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in subjects with gestational diabetes mellitus (GDM) and investigate the relationships between CEACAM1 and GDM. Circulating CEACAM1 levels were measured by ELISA kit in 70 women with GDM and 70 normal glucose tolerance (NGT) pregnant women. Blood samples were collected to detect fasting plasma glucose (FPG), fasting insulin (FINS) and glycosylated hemoglobin (HbA1c) levels in all participants. Insulin sensitivity index (ISOGTT) was calculated to assess insulin sensitivity.

Correlation analysis was performed between serum CEACAM1 levels and other parameters.Circulating CEACAM1 levels were higher in the GDM group than that in the NGT pregnant group, however, the difference showed no statistical significance (1889.82 ± 616.14 vs 1758.92 ± 433.15 pg/ml, p > 0.05). In GDM group, CEACAM1 was positively correlated with ISOGTT (R = 0.39, P = 0.001), while negatively with 1 h post-meal plasma insulin level (1hPINS) (R = -0.32, P = 0.008), 2 h post-meal plasma insulin level (2hPINS) (R = -0.33, P = 0.006) and area under curve of insulin (AUCI) (R = -0.36, P = 0.002) when adjusting for maternal age and gestational age.

The present study showed that circulating CEACAM1 levels did not differ in both GDM and NGT groups. However, we found a significant positively correlation between CEACAM1 and insulin sensitivity in the GDM group.

DACH1, a novel target of miR-218, participates in the regulation of cell viability, apoptosis, inflammatory response, and epithelial-mesenchymal transition process in renal tubule cells treated by high-glucose.

Objective: This report was designed to assess the functional role of miR-218/dachshund family transcription factor 1 (DACH1) in diabetic kidney disease (DKD) and investigate its possible molecular mechanism.Materials and Methods: From the GEO database, we downloaded different datasets for analyzing the expression of miR-218 and DACH1 in DKD. TargetScan was adopted to predict the binding sites between miR-218 and DACH1, which was further verified by dual-luciferase reporter assays. The renal proximal tubule cells (HK-2) treated with high glucose (HG) were used as an in vitro model.

QRT-PCR and western blot were used to determine the expression of DACH1 and other relative factors. Cell counting kit-8 and flow cytometer were applied to detect cell viability and apoptosis. The levels of inflammatory cytokines were determined by an ELISA assay.

CD314 (NKG2D) Antibody
abx201090-01mg	Abbexa	0.1 mg	EUR 398

Anti-NKG2D Antibody
STJ501924	St John's Laboratory	100 µg	EUR 476

CD314 (NKG2D)
314A-100T	ImmunoStep	100 test	EUR 609

CD314 (NKG2D)
314B-01MG	ImmunoStep	0,1 mg	EUR 284

CD314 (NKG2D)
314F-100T	ImmunoStep	100 test	EUR 375

CD314 (NKG2D)
314PE-100T	ImmunoStep	100 test	EUR 700

CD314 (NKG2D)
314PU-01MG	ImmunoStep	0,1 mg	EUR 297

CD314 (NKG2D)
MO314B(V50)	ImmunoStep	50 ug	EUR 50

CD314 (NKG2D)
MO314F(V50)	ImmunoStep	50 ug	EUR 50

CD314 (NKG2D)
MO314PE(V50)	ImmunoStep	50 ug	EUR 50

Anti-NKG2D/KLRK1 Antibody
A00661-1	BosterBio	100ug/vial	EUR 294

CD314 (NKG2D) Antibody (FITC)
abx201091-100tests	Abbexa	100 tests	EUR 467

CD314 (NKG2D) Antibody (PE)
abx201092-100tests	Abbexa	100 tests	EUR 773

CD314 (NKG2D) Antibody (APC)
abx201093-100tests	Abbexa	100 tests	EUR 690

CD314 (NKG2D) Antibody (Biotin)
abx201094-01mg	Abbexa	0.1 mg	EUR 384

Anti-NKG2D Antibody BIOTIN
STJ501925	St John's Laboratory	100 µg	EUR 586

Anti-NKG2D Antibody FITC
STJ501926	St John's Laboratory	100 µg	EUR 586

Anti-NKG2D / KLRK1 antibody
STJ70739	St John's Laboratory	100 µg	EUR 359

NKG2D Polyclonal Conjugated Antibody
C46825	SAB	100ul	EUR 397

NKG2D Ligand 2 (ULBP2) Antibody
20-abx320552	Abbexa	EUR 300.00 EUR 244.00	100 ul 50 ul

NKG2D Ligand 2 (ULBP2) Antibody
abx239250-100ug	Abbexa	100 ug	EUR 551

NKG2D Ligand 2 (ULBP2) Antibody
20-abx142298	Abbexa	EUR 370.00 EUR 606.00 EUR 314.00	100 ul 200 ul 50 ul

NKG2D Ligand 2 (ULBP2) Antibody
20-abx005773	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

NKG2D Ligand 2 (ULBP2) Antibody
abx029272-400ul	Abbexa	400 ul	EUR 523

NKG2D Ligand 2 (ULBP2) Antibody
abx029272-80l	Abbexa	80 µl	EUR 286

Polyclonal Goat Anti-NKG2D / KLRK1 Antibody
APG00220G	Leading Biology	0.1mg	EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-NKG2D / KLRK1 . This antibody is tested and proven to work in the following applications:

Human soluble NKG2D ligands ELISA kit
E01N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Human soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human soluble NKG2D ligands ELISA kit
E01N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Human soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human soluble NKG2D ligands ELISA kit
E01N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Human soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse soluble NKG2D ligands ELISA kit
E03N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse soluble NKG2D ligands ELISA kit
E03N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse soluble NKG2D ligands ELISA kit
E03N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat soluble NKG2D ligands ELISA kit
E02N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat soluble NKG2D ligands ELISA kit
E02N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Rat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat soluble NKG2D ligands ELISA kit
E02N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Rat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble NKG2D ligands ELISA kit
E06N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble NKG2D ligands ELISA kit
E06N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Goat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble NKG2D ligands ELISA kit
E06N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Goat soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog soluble NKG2D ligands ELISA kit
E08N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog soluble NKG2D ligands ELISA kit
E08N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Canine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog soluble NKG2D ligands ELISA kit
E08N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Canine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig soluble NKG2D ligands ELISA kit
E07N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig soluble NKG2D ligands ELISA kit
E07N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig soluble NKG2D ligands ELISA kit
E07N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit soluble NKG2D ligands ELISA kit
E04N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit soluble NKG2D ligands ELISA kit
E04N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit soluble NKG2D ligands ELISA kit
E04N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey soluble NKG2D ligands ELISA kit
E09N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey soluble NKG2D ligands ELISA kit
E09N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey soluble NKG2D ligands ELISA kit
E09N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant Human NKG2D/CD314/KLRK1 Protein
RP00417	Abclonal	10 μg	EUR 174

Armenian Hamster Anti-Mouse NKG2D Monoclonal antibody, clone HMG2D
CABT-L4409-1mg	Creative Diagnostics	1 mg	EUR 897

Armenian Hamster Anti-Mouse NKG2D Monoclonal antibody, clone HMG2D
CABT-L4409-5mg	Creative Diagnostics	5 mg	EUR 2405

NKG2-D Type II Integral Membrane Protein (NKG2D) Antibody
abx430571-200ul	Abbexa	200 ul	EUR 384

Human NKG2D ligand 3, ULBP3 ELISA KIT
ELI-16826h	Lifescience Market	96 Tests	EUR 824

Human NKG2D ligand 2, ULBP2 ELISA KIT
ELI-07220h	Lifescience Market	96 Tests	EUR 824

Human NKG2D ligand 1, ULBP1 ELISA KIT
ELI-44017h	Lifescience Market	96 Tests	EUR 824

Human NKG2D ligand 3(ULBP3) ELISA kit
CSB-EL025611HU-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 3 (ULBP3) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human NKG2D ligand 3(ULBP3) ELISA kit
1-CSB-EL025611HU	Cusabio	EUR 804.00 EUR 5099.00 EUR 2704.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 3(ULBP3) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human NKG2D ligand 4(RAET1E) ELISA kit
CSB-EL019277HU-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 4 (RAET1E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human NKG2D ligand 4(RAET1E) ELISA kit
1-CSB-EL019277HU	Cusabio	EUR 804.00 EUR 5099.00 EUR 2704.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human NKG2D ligand 4(RAET1E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human NKG2D ligand 4, RAET1E ELISA KIT
ELI-38378h	Lifescience Market	96 Tests	EUR 824

Guinea pig soluble NKG2D ligands ELISA kit
E05N0038-192T	BlueGene	192 tests	EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig soluble NKG2D ligands ELISA kit
E05N0038-48	BlueGene	1 plate of 48 wells	EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig soluble NKG2D ligands ELISA kit
E05N0038-96	BlueGene	1 plate of 96 wells	EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig soluble NKG2D ligands in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human NKG2D ligand 2 (ULBP2) ELISA Kit
abx251525-96tests	Abbexa	96 tests	EUR 668

Human ULBP2/ NKG2D ligand 2 ELISA Kit
E2641Hu	Sunlong	1 Kit	EUR 571

ELISA kit for Human NKG2D ligand 2
EK4447	SAB	96 tests	EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human NKG2D ligand 2 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human ULBP2(NKG2D ligand 2) ELISA Kit
EH2185	FN Test	96T	EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 7.5IU/ml

Human NKG2D Protein (Ile 73-Val 216) [Fc]
VAng-2608Lsx-100g	Creative Biolabs	100 µg	EUR 875
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1)

Human NKG2D Protein (Ile 73-Val 216) [Fc]
VAng-2608Lsx-1mg	Creative Biolabs	1 mg	EUR 5494
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1)

Human NKG2D Protein (Ile 73-Val 216) [His]
VAng-2609Lsx-100g	Creative Biolabs	100 µg	EUR 875
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1)

Human NKG2D Protein (Ile 73-Val 216) [His]
VAng-2609Lsx-1mg	Creative Biolabs	1 mg	EUR 5494
Description: Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1)

ELISA kit for Human NKG2D ligand 4 (RAET1E)
KTE60982-48T	Abbkine	48T	EUR 332
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 4 (RAET1E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human NKG2D ligand 4 (RAET1E)
KTE60982-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2115
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 4 (RAET1E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human NKG2D ligand 4 (RAET1E)
KTE60982-96T	Abbkine	96T	EUR 539
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 4 (RAET1E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human NKG2D ligand 2 (ULBP2)
KTE60089-48T	Abbkine	48T	EUR 332
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 2 (ULBP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human NKG2D ligand 2 (ULBP2)
KTE60089-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2115
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 2 (ULBP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human NKG2D ligand 2 (ULBP2)
KTE60089-96T	Abbkine	96T	EUR 539
Description: Quantitative sandwich ELISA for measuring Human NKG2D ligand 2 (ULBP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His)
C508-10ug	Novoprotein	10ug	EUR 121
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His)
C508-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His)
C508-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-6His)
C508-50ug	Novoprotein	50ug	EUR 263
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc)
CK50-10ug	Novoprotein	10ug	EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc)
CK50-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc)
CK50-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-Fc)
CK50-50ug	Novoprotein	50ug	EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His)
CK78-10ug	Novoprotein	10ug	EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His)
CK78-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His)
CK78-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His)
CK78-50ug	Novoprotein	50ug	EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc)
CX42-10ug	Novoprotein	10ug	EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc)
CX42-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc)
CX42-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc)
CX42-50ug	Novoprotein	50ug	EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc)
CU41-10ug	Novoprotein	10ug	EUR 141
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc)
CU41-1mg	Novoprotein	1mg	EUR 1674
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc)
CU41-500ug	Novoprotein	500ug	EUR 1186
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Natural Killer G2D/NKG2D/CD314/KLRK1 (N-Fc)
CU41-50ug	Novoprotein	50ug	EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Human NKG2D Protein (Ile 73-Val 216) [His] (HPLC-verified)
VAng-2607Lsx-100g	Creative Biolabs	100 µg	EUR 875
Description: Human NKG2D (CD314) protein, His tag, HPLC-verified, was expressed in human 293 cells. (Uniprot ID: P26718-1)

Human NKG2D Protein (Ile 73-Val 216) [His] (HPLC-verified)
VAng-2607Lsx-1mg	Creative Biolabs	1 mg	EUR 5494
Description: Human NKG2D (CD314) protein, His tag, HPLC-verified, was expressed in human 293 cells. (Uniprot ID: P26718-1)

Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)
CP46-10ug	Novoprotein	10ug	EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)
CP46-1mg	Novoprotein	1mg	EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)
CP46-500ug	Novoprotein	500ug	EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)
CP46-50ug	Novoprotein	50ug	EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

H2B Antibody Antibody
AF4659	Affbiotech	200ul	EUR 376
Description: H2B Antibody Antibody detects endogenous levels of H2B.

CD11b Antibody Antibody
ABD2911	Lifescience Market	100 ug	EUR 438

anti- Antibody^Polyclonal antibody control antibody
LSMab09882	Lifescience Market	100 ug	EUR 438

Ly1 Antibody Reactive (LYAR) Antibody
20-abx123734	Abbexa	EUR 411.00 EUR 592.00	100 ul 200 ul

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319900	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319901	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319905	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319913	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Ly1 Antibody Reactive (LYAR) Antibody
20-abx311665	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Ly1 Antibody Reactive (LYAR) Antibody
abx234901-100ug	Abbexa	100 ug	EUR 551

Anti-Glycolipid Antibody (AGA) Antibody
abx230204-100ug	Abbexa	100 ug	EUR 481

Ly1 Antibody Reactive (LYAR) Antibody
20-abx324434	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Anti-Glycolipid Antibody (AGA) Antibody
20-abx004855	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Anti-Glycolipid Antibody (AGA) Antibody
abx036399-100ug	Abbexa	100 ug	EUR 391

Ly1 Antibody Reactive (LYAR) Antibody
20-abx008109	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Ly1 Antibody Reactive (LYAR) Antibody
20-abx014333	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Ly1 Antibody Reactive (LYAR) Antibody
abx033330-400ul	Abbexa	400 ul	EUR 523

Ly1 Antibody Reactive (LYAR) Antibody
abx033330-80l	Abbexa	80 µl	EUR 286

Anti-Anti-SEPT2 Antibody antibody
STJ25475	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT5 Antibody antibody
STJ25477	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody
STJ25479	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody
STJ28365	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT7 Antibody antibody
STJ28963	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody
STJ117206	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody
STJ117759	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody
STJ118549	St John's Laboratory	100 µl	EUR 277

Anti-Anti-MARCH6 Antibody antibody
STJ118550	St John's Laboratory	100 µl	EUR 277

Anti-Anti-MARCH7 Antibody antibody
STJ118752	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT3 Antibody antibody
STJ118990	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT1 antibody antibody
STJ119580	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody
STJ116214	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody
STJ11100949	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody
STJ111369	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody
STJ111530	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT4 Antibody antibody
STJ112276	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody
STJ112609	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT11 Antibody antibody
STJ113941	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT11 Antibody antibody
STJ114081	St John's Laboratory	100 µl	EUR 277

Anti-Anti-SEPT5 Antibody antibody
STJ114819	St John's Laboratory	100 µl	EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody
STJ114828	St John's Laboratory	100 µl	EUR 277

Antibody Pair to ApoA-V antibody
10R-1876	Fitzgerald	100 ul	EUR 651
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody

Goat anti- human Antibody^Polyclonal antibody
LSMab09896	Lifescience Market	100 ug	EUR 438

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319902	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319903	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319904	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319906	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319907	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319908	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319914	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319915	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319916	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319929	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319930	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319931	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (HRP)
20-abx311666	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Results: A prominent raise of miR-218 was observed in DKD through bioinformatics analysis, which was further confirmed in the HG-induced model. DACH1 is a target of miR-218. miR-218 reduced cell viability and induced apoptosis by negatively regulating DACH1. Moreover, upregulating miR-218 in HG models increased the concentrations of pro-inflammatory cytokines TNF-α and IL-1β, reduced the level of anti-inflammatory cytokine IL-10, and promoted the epithelial-mesenchymal transition (EMT) process, which is possibly achieved by targeting DACH1.

While downregulating miR-218 showed the opposite results.Conclusion: These data demonstrated that, under an in vitro HG environment, miR-218 suppressed the HK-2 cells proliferation, promoted apoptosis, caused an inflammatory response, and facilitated the EMT process largely by targeting DACH1, providing an insight into the therapeutic intervention of DKD.